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SMARCA2 and KHDRBS1
Number of citations of the paper that reports this interaction (PMID
16341228
)
126
Data Source:
BioGRID
(pull down)
HPRD
(in vivo, in vitro)
SMARCA2
KHDRBS1
Gene Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
KH domain containing, RNA binding, signal transduction associated 1
Image
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
SWI/SNF Complex
Intracellular Membrane-bounded Organelle
Intermediate Filament Cytoskeleton
NpBAF Complex
NBAF Complex
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Grb2-Sos Complex
Molecular Function
RNA Polymerase II Transcription Coactivator Activity
Transcription Coactivator Activity
Helicase Activity
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Histone Binding
Transcription Regulatory Region DNA Binding
DNA Binding
RNA Binding
SH3/SH2 Adaptor Activity
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
SH3 Domain Binding
Protein Complex Binding
Identical Protein Binding
Poly(A) RNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Chromatin Remodeling
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Nervous System Development
Negative Regulation Of Cell Proliferation
Negative Regulation Of Cell Growth
Aortic Smooth Muscle Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
G2/M Transition Of Mitotic Cell Cycle
Transcription, DNA-templated
MRNA Processing
Cell Cycle Arrest
Signal Transduction
Cell Surface Receptor Signaling Pathway
Cell Proliferation
Positive Regulation Of Signal Transduction
Regulation Of Protein Stability
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Translational Initiation
Regulation Of RNA Export From Nucleus
Positive Regulation Of RNA Export From Nucleus
Pathways
Chromatin modifying enzymes
Chromatin organization
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) (
23453885
)
Protein-Protein Interactions
26 interactors:
ACTL6A
ACTL6B
AR
ARID1B
BEND7
BRCA1
CEBPA
DPF3
ESR1
HIST1H3A
KHDRBS1
MDM2
MDM4
MECP2
MYB
MYC
NR0B2
NR3C1
NR4A2
PHB
PITX1
PRMT5
PRPF6
SDCBP
SIN3B
SS18
109 interactors:
ABI2
ACTB
AGO1
AHI1
AMPH
APBB1
ARHGEF4
ARHGEF9
AZIN1
BAIAP2L1
BTK
BZRAP1
CBL
CD2AP
CDK1
CIRBP
CREB3L3
CREBBP
CRK
CRKL
CSK
DDX5
DHX9
DLG1
DLG2
DLG3
DLG4
DNMBP
DOCK2
DOCK3
EFEMP1
EMG1
FGR
FNBP4
FRK
FYN
GAS7
GPHN
GRAP
GRAP2
GRB2
HCK
HNRNPK
INSR
ITK
ITSN1
ITSN2
JAK3
KHDRBS3
LCK
LYN
MAPK1
MIA2
MPP6
MYO1C
MYO7A
NCF1
NCK1
NCK2
NCKIPSD
NPHP1
OSTF1
PACSIN1
PIK3R1
PIK3R3
PLCG1
PLCG2
POT1
PPP1R13B
PRMT1
PSTPIP1
PTBP2
PTK6
PTPN6
RALY
RAPSN
RASA1
RBFOX2
RBM7
RBMX
RUSC2
SASH1
SCG5
SH3PXD2A
SH3YL1
SKAP2
SMAD2
SMARCA2
SNX30
SNX9
SORBS1
SPATA13
SRC
SSFA2
STAT3
STUB1
TBL1X
TJP1
TNFSF11
TUBB3
U2AF2
UBA52
UBASH3B
VAV1
WBP4
YES1
YTHDC1
ZBTB7A
ZDHHC6
Entrez ID
6595
10657
HPRD ID
02483
03926
Ensembl ID
ENSG00000080503
ENSG00000121774
Uniprot IDs
P51531
Q56A76
Q8N9Q1
Q07666
PDB IDs
2DAT
2XA6
3QHE
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
Chromatin Organization
RNA Metabolic Process
Chromatin Modification
Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Chromosome Organization
Negative Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Organelle Organization
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Cyclic Compound
Intracellular Steroid Hormone Receptor Signaling Pathway
Response To Steroid Hormone
Cellular Response To Steroid Hormone Stimulus
Transcription Initiation From RNA Polymerase II Promoter
Chromatin Remodeling
Developmental Process
Negative Regulation Of Cellular Metabolic Process
Intracellular Receptor Signaling Pathway
Regulation Of Cellular Process
Steroid Hormone Mediated Signaling Pathway
Anatomical Structure Development
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Fc Receptor Signaling Pathway
Signaling
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Communication
Peptidyl-tyrosine Autophosphorylation
Innate Immune Response
Signal Transduction
Immune Response-regulating Signaling Pathway
Immune Response
Endocytosis
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Locomotion
Movement Of Cell Or Subcellular Component
Cellular Response To Stimulus
Positive Regulation Of Metabolic Process
Cell Surface Receptor Signaling Pathway
Defense Response
Positive Regulation Of Immune Response
Regulation Of Immune System Process
Cellular Response To Peptide Hormone Stimulus
Neurotrophin TRK Receptor Signaling Pathway
Phagocytosis
Cellular Response To Peptide
Positive Regulation Of Immune System Process
Neurotrophin Signaling Pathway
Positive Regulation Of Signal Transduction
Cellular Response To Growth Factor Stimulus
Regulation Of Immune Response
Epidermal Growth Factor Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Growth Factor
Antigen Receptor-mediated Signaling Pathway
Cell Differentiation
Regulation Of Catalytic Activity
Regulation Of Signal Transduction
Peptidyl-tyrosine Phosphorylation
Regulation Of Cellular Component Organization
Immune System Process
Response To Stimulus
Regulation Of Signaling
Cell Projection Organization
Intracellular Signal Transduction
Cellular Response To Organic Substance
Regulation Of Metabolic Process
Tagcloud
?
abnormality
arid1a
coinactivation
copyright
fish
frame
harboring
heterozygous
infancy
insights
malignancies
missense
monoploid
mrts
pbrm1
protected
remodeling
reserved
rhabdoid
rights
screened
sense
snf
subunits
swi
trisomy
truncating
Tagcloud (Difference)
?
abnormality
arid1a
coinactivation
copyright
fish
frame
harboring
heterozygous
infancy
insights
malignancies
missense
monoploid
mrts
pbrm1
protected
remodeling
reserved
rhabdoid
rights
screened
sense
snf
subunits
swi
trisomy
truncating
Tagcloud (Intersection)
?