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SMARCA2 and PRPF6
Number of citations of the paper that reports this interaction (PMID
16341228
)
126
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
SMARCA2
PRPF6
Gene Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
pre-mRNA processing factor 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
SWI/SNF Complex
Intracellular Membrane-bounded Organelle
Intermediate Filament Cytoskeleton
NpBAF Complex
NBAF Complex
Nucleus
Nucleoplasm
Spliceosomal Complex
U5 SnRNP
Membrane
Nuclear Speck
U4/U6 X U5 Tri-snRNP Complex
U4/U6 SnRNP
Catalytic Step 2 Spliceosome
Molecular Function
RNA Polymerase II Transcription Coactivator Activity
Transcription Coactivator Activity
Helicase Activity
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Histone Binding
Transcription Regulatory Region DNA Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
Ribonucleoprotein Complex Binding
Poly(A) RNA Binding
Androgen Receptor Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Chromatin Remodeling
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Nervous System Development
Negative Regulation Of Cell Proliferation
Negative Regulation Of Cell Growth
Aortic Smooth Muscle Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Spliceosomal Tri-snRNP Complex Assembly
Spliceosomal Complex Assembly
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
RNA Localization
RNA Splicing
Gene Expression
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Chromatin modifying enzymes
Chromatin organization
RMTs methylate histone arginines
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) (
23453885
)
Prostate cancer (
23535732
)
Protein-Protein Interactions
26 interactors:
ACTL6A
ACTL6B
AR
ARID1B
BEND7
BRCA1
CEBPA
DPF3
ESR1
HIST1H3A
KHDRBS1
MDM2
MDM4
MECP2
MYB
MYC
NR0B2
NR3C1
NR4A2
PHB
PITX1
PRMT5
PRPF6
SDCBP
SIN3B
SS18
13 interactors:
AR
ARAF
CD2BP2
EFTUD2
ESR1
NR3C1
RAF1
SMARCA2
SRRM2
TIMM44
TXNL4A
TXNL4B
YWHAB
Entrez ID
6595
24148
HPRD ID
02483
10729
Ensembl ID
ENSG00000080503
ENSG00000101161
Uniprot IDs
P51531
Q56A76
Q8N9Q1
O94906
PDB IDs
2DAT
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
Chromatin Organization
RNA Metabolic Process
Chromatin Modification
Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Chromosome Organization
Negative Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Organelle Organization
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Cyclic Compound
Intracellular Steroid Hormone Receptor Signaling Pathway
Response To Steroid Hormone
Cellular Response To Steroid Hormone Stimulus
Transcription Initiation From RNA Polymerase II Promoter
Chromatin Remodeling
Developmental Process
Negative Regulation Of Cellular Metabolic Process
Intracellular Receptor Signaling Pathway
Regulation Of Cellular Process
Steroid Hormone Mediated Signaling Pathway
Anatomical Structure Development
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Splicing
Gene Expression
MRNA Processing
Intracellular Steroid Hormone Receptor Signaling Pathway
RNA Metabolic Process
MRNA Metabolic Process
Cellular Response To Hormone Stimulus
RNA Processing
Cellular Metabolic Process
Steroid Hormone Mediated Signaling Pathway
Hormone-mediated Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of Cell Death
Response To Hormone
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Ribonucleoprotein Complex Assembly
Nucleobase-containing Compound Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA-templated Transcription, Initiation
Cellular Nitrogen Compound Metabolic Process
Cellular Component Assembly
Mammary Gland Duct Morphogenesis
Spliceosomal Complex Assembly
Nitrogen Compound Metabolic Process
Organelle Organization
Death-inducing Signaling Complex Assembly
Negative Regulation Of Integrin Biosynthetic Process
Glucocorticoid Mediated Signaling Pathway
Activation Of MAPKK Activity
Negative Regulation Of Dephosphorylation
Prostate Gland Development
Ribonucleoprotein Complex Biogenesis
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Peptidyl-serine Phosphorylation
Metabolic Process
Mammary Gland Morphogenesis
Positive Regulation Of Phosphorylation
Positive Regulation Of Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Cellular Biosynthetic Process
Aortic Smooth Muscle Cell Differentiation
Mammary Gland Epithelium Development
Cellular Response To Lipid
Tagcloud
?
abnormality
arid1a
coinactivation
copyright
fish
frame
harboring
heterozygous
infancy
insights
malignancies
missense
monoploid
mrts
pbrm1
protected
remodeling
reserved
rhabdoid
rights
screened
sense
snf
subunits
swi
trisomy
truncating
Tagcloud (Difference)
?
abnormality
arid1a
coinactivation
copyright
fish
frame
harboring
heterozygous
infancy
insights
malignancies
missense
monoploid
mrts
pbrm1
protected
remodeling
reserved
rhabdoid
rights
screened
sense
snf
subunits
swi
trisomy
truncating
Tagcloud (Intersection)
?