SLC6A12 and ERBB2IP

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		SLC6A12	ERBB2IP
Gene Name		solute carrier family 6 (neurotransmitter transporter), member 12	erbb2 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane
	Molecular Function	Neurotransmitter:sodium Symporter Activity Gamma-aminobutyric Acid:sodium Symporter Activity	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Transport Ion Transport Amino Acid Transport Synaptic Transmission Neurotransmitter Secretion Cellular Water Homeostasis Response To Organic Substance Gamma-aminobutyric Acid Transport Transmembrane Transport Cellular Hyperosmotic Response	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Pathways		Na+/Cl- dependent neurotransmitter transporters Transport of inorganic cations/anions and amino acids/oligopeptides Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds GABA synthesis, release, reuptake and degradation SLC-mediated transmembrane transport Metabolism of amino acids and derivatives Reuptake of GABA Neurotransmitter Release Cycle Amino acid transport across the plasma membrane Creatine metabolism Transmission across Chemical Synapses	Signaling by ERBB2
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Metabolite levels ( 23378610)
Protein-Protein Interactions		3 interactors: ERBB2IP LIN7A REL	62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9
Entrez ID		6539	55914
HPRD ID		04358	06090
Ensembl ID		ENSG00000111181	ENSG00000112851
Uniprot IDs		P48065	B4DIP2 Q96RT1
PDB IDs			1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Cell Polarity Basal Protein Localization Protein Localization To Basolateral Plasma Membrane Maintenance Of Epithelial Cell Apical/basal Polarity Maintenance Of Apical/basal Cell Polarity Positive Regulation Of Interleukin-12 Biosynthetic Process Maintenance Of Cell Polarity Regulation Of Interleukin-12 Biosynthetic Process	Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway
Tagcloud ?			adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Difference) ?			adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Intersection) ?