SLC6A12

Gene Name		solute carrier family 6 (neurotransmitter transporter), member 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Neurotransmitter:sodium Symporter Activity Gamma-aminobutyric Acid:sodium Symporter Activity
	Biological Process	Transport Ion Transport Amino Acid Transport Synaptic Transmission Neurotransmitter Secretion Cellular Water Homeostasis Response To Organic Substance Gamma-aminobutyric Acid Transport Transmembrane Transport Cellular Hyperosmotic Response
Pathways		Na+/Cl- dependent neurotransmitter transporters Transport of inorganic cations/anions and amino acids/oligopeptides Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds GABA synthesis, release, reuptake and degradation SLC-mediated transmembrane transport Metabolism of amino acids and derivatives Reuptake of GABA Neurotransmitter Release Cycle Amino acid transport across the plasma membrane Creatine metabolism Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Metabolite levels ( 23378610)
Protein-protein Interactions		3 interactors: ERBB2IP LIN7A REL
Entrez ID		6539
HPRD ID		04358
Ensembl ID		ENSG00000111181
Uniprot IDs		P48065
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Cell Polarity Basal Protein Localization Protein Localization To Basolateral Plasma Membrane Maintenance Of Epithelial Cell Apical/basal Polarity Maintenance Of Apical/basal Cell Polarity Positive Regulation Of Interleukin-12 Biosynthetic Process Maintenance Of Cell Polarity Regulation Of Interleukin-12 Biosynthetic Process
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