SLC6A12

Description		solute carrier family 6 member 12
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Cell Projection Presynapse
	Molecular Function	Gamma-aminobutyric Acid:sodium:chloride Symporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity
	Biological Process	Amino Acid Transmembrane Transport Neurotransmitter Transport Amino Acid Transport Monocarboxylic Acid Transport Gamma-aminobutyric Acid Transport Glycine Betaine Transport Sodium Ion Transmembrane Transport Gamma-aminobutyric Acid Reuptake
Pathways		Amino acid transport across the plasma membrane Creatine metabolism Reuptake of GABA
Drugs		Guvacine
Diseases
GWAS		Chronic kidney disease ( 20383146) Diisocyanate-induced asthma ( 25918132) Metabolite levels ( 23378610 23823483) Serum metabolite levels ( 33031748)
Interacting Genes		4 interacting genes: CD79A ERBIN LIN7A REL
Entrez ID		6539
HPRD ID		04358
Ensembl ID		ENSG00000111181
Uniprot IDs		P48065
PDB IDs
Enriched GO Terms of Interacting Partners?		IgM B Cell Receptor Complex B Cell Receptor Complex NF-kappaB Complex L27 Domain Binding Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway ErbB-2 Class Receptor Binding Basal Protein Localization MPP7-DLG1-LIN7 Complex Basolateral Plasma Membrane Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Cytokine Production Regulation Of Synaptic Assembly At Neuromuscular Junction Hemidesmosome Postsynaptic Specialization Negative Regulation Of Interferon-beta Production Anchoring Junction Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Tagcloud ?