VPS33A and VPS11

Number of citations of the paper that reports this interaction (PubMedID 11382755)
0

Data Source:
HPRD (in vivo)

		VPS33A	VPS11
Description		VPS33A core subunit of CORVET and HOPS complexes	VPS11 core subunit of CORVET and HOPS complexes
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Endosome Membrane Membrane AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Cytoplasmic Vesicle Late Endosome Membrane CORVET Complex Perinuclear Region Of Cytoplasm Clathrin Complex	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Endosome Membrane Membrane Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Cytoplasmic Vesicle Late Endosome Membrane CORVET Complex Vesicle Tethering Complex
	Molecular Function	Protein Binding	Nucleotide Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Intracellular Protein Transport Autophagy Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Platelet Formation Melanosome Localization Lysosome Localization Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Regulation Of Lysosomal Lumen PH Pigmentation Regulation Of Developmental Pigmentation Autophagosome Maturation	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Positive Regulation Of Protein Catabolic Process Organelle Fusion Regulation Of Organelle Assembly Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		SARS-CoV-2 modulates autophagy	SARS-CoV-2 modulates autophagy
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Adult body size ( 32376654) Body mass index ( 29273807) Coronary artery disease ( 29212778 33020668) HDL cholesterol levels ( 32203549) Plateletcrit ( 32888494)
Interacting Genes		7 interacting genes: MON1A MON1B ROPN1 TNKS VPS11 VPS16 VPS18	33 interacting genes: BCAR1 BMI1 ECPAS EZR GGA3 GRSF1 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MARK3 MON1B MSN RAB7A RDX RILP RNF181 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS45
Entrez ID		65082	55823
HPRD ID		15651	12258
Ensembl ID		ENSG00000139719	ENSG00000160695
Uniprot IDs		F5H6Y0 Q96AX1	A0A087WXL6 B7Z879 Q9H270
PDB IDs		4BX8 4BX9
Enriched GO Terms of Interacting Partners?		Vacuolar Transport CORVET Complex Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion HOPS Complex Intracellular Protein Localization Protein Transport Intracellular Protein Transport Vesicle Tethering Complex Establishment Of Protein Localization Endosome To Lysosome Transport Mon1-Ccz1 Complex Clathrin-coated Vesicle Autophagosome Vesicle Fusion Organelle Membrane Fusion Lysosomal Transport Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Organelle Fusion Vesicle-mediated Transport Late Endosome Membrane Late Endosome Membrane Fusion Intracellular Transport Vacuole Organization Protein Localization To Organelle Cellular Localization Regulation Of Intracellular Estrogen Receptor Signaling Pathway Establishment Of Localization In Cell Vesicle Docking Involved In Exocytosis Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Endosome Membrane Syntaxin Binding Autophagy Protein Targeting To Vacuole Vesicle Organization Early Endosome Vesicle Docking Establishment Of Protein Localization To Vacuole Lysosomal Membrane Organelle Localization By Membrane Tethering Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Endosome Organization Regulation Of Protein-containing Complex Assembly Membrane Docking Protein Localization To Vacuole Lysosome Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Telomeric Early Viral Transcription Vacuole Fusion, Non-autophagic	Late Endosome Membrane Docking Vesicle Organization Organelle Membrane Fusion Vesicle Fusion Organelle Fusion Endosome Vesicle-mediated Transport Intracellular Protein Transport Membrane Fusion Early Endosome Vacuolar Transport Endosome To Lysosome Transport Intracellular Protein Localization Lysosomal Transport Positive Regulation Of Catabolic Process Establishment Of Protein Localization Protein Transport Organelle Localization Macromolecule Catabolic Process Catabolic Process Vesicle Docking SNARE Binding Regulation Of Protein Localization Positive Regulation Of Protein Catabolic Process Cellular Localization Chloride Channel Inhibitor Activity CORVET Complex Clathrin-coated Vesicle Intracellular Transport Organelle Localization By Membrane Tethering Positive Regulation Of Early Endosome To Late Endosome Transport Autophagosome Membrane Organization Endosome Organization Late Endosome Membrane Positive Regulation Of Protein Localization To Early Endosome SNAP Receptor Activity Endosomal Transport Positive Regulation Of Protein Localization To Endosome Establishment Of Localization In Cell Endosome Membrane SNARE Complex HOPS Complex Autophagy Autophagosome Maturation Syntaxin Binding Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Positive Regulation Of Protein Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?