LLGL1 and STX4

Number of citations of the paper that reports this interaction (PMID 18793635)
7

Data Source:
HPRD (in vivo)

		LLGL1	STX4
Gene Name		lethal giant larvae homolog 1 (Drosophila)	syntaxin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Cis Cisterna Golgi Membrane Cytoplasm Cytoskeleton Axon Cortical Actin Cytoskeleton Early Endosome Membrane Trans-Golgi Network Membrane Myelin Sheath Abaxonal Region	Extracellular Space Intracellular Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Rab GTPase Activator Activity Structural Molecule Activity Protein Binding Protein Kinase Binding	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process	Protein Complex Assembly Exocytosis Golgi To Plasma Membrane Transport Axonogenesis Cortical Actin Cytoskeleton Organization Positive Regulation Of Rab GTPase Activity Maintenance Of Apical/basal Cell Polarity	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Blood Coagulation Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Platelet Activation Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Membrane Organization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways			Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ACD CACNA1A CD46 STX4	48 interactors: ACTB BET1 CYBRD1 DLG1 GIMAP5 GOSR2 ITSN2 LLGL1 NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPT5 SNAP23 SNAP25 SNAP29 SNAP47 STX12 STX16 STX3 STX5 STX6 STX7 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VAPB VTI1B
Entrez ID		3996	6810
HPRD ID		02982	01722
Ensembl ID		ENSG00000131899	ENSG00000103496
Uniprot IDs		Q15334	A8MXY0 B7Z425 Q12846
PDB IDs
Enriched GO Terms of Interacting Partners?		Neurotransmitter Secretion Positive Regulation Of Single-stranded Telomeric DNA Binding Cerebellar Molecular Layer Development Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Vestibular Nucleus Development Positive Regulation Of Eosinophil Degranulation Regulation Of Insulin Secretion Response To Stress Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Regulation Of Peptide Hormone Secretion Gamma-aminobutyric Acid Secretion Regulation Of Hormone Secretion Cellular Protein Localization Interleukin-10 Production Regulation Of Acetylcholine Secretion, Neurotransmission Telomere Assembly Protection From Non-homologous End Joining At Telomere Positive Regulation Of Regulatory T Cell Differentiation Telomere Capping Rhythmic Synaptic Transmission Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Memory T Cell Differentiation Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cell Activation Regulation Of Synaptic Transmission Positive Regulation Of Telomerase Activity Exocytosis Positive Regulation Of Protein Localization To Cell Surface Sequestering Of Extracellular Ligand From Receptor Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Positive Regulation Of Immunoglobulin Secretion Positive Regulation Of Cell Adhesion Regulation Of Vesicle-mediated Transport Gamma-aminobutyric Acid Transport Regulation Of Memory T Cell Differentiation Chloride Ion Homeostasis Regulation Of Protein Secretion Negative Regulation Of Telomere Maintenance SNARE Complex Assembly Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Hormone Biosynthetic Process Regulation Of Telomere Maintenance Via Telomerase Pons Development Cellular Component Assembly Protein Localization Regulation Of Cellular Component Organization	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization Vesicle Organization Establishment Of Localization In Cell Cellular Localization Exocytosis Secretion By Cell Secretion Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Cellular Localization Vesicle Docking Regulation Of Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Docking Regulation Of Neurotransmitter Levels Intracellular Protein Transport Neurotransmitter Transport Synaptic Vesicle Exocytosis Vesicle Fusion With Golgi Apparatus Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Secretion Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Organelle Organization Endomembrane System Organization Cytoplasmic Transport SNARE Complex Assembly Endosomal Transport Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Establishment Of Organelle Localization Synaptic Transmission Golgi To Plasma Membrane Transport Regulation Of Protein Localization ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Exocytosis
Tagcloud ?		apical blastocyst cdx2 compaction dampened derives erm gtpases hippo icm lats1 lineages nanog outer pard6b phosphorylating polarity polarization prkcz rho rock scrib segregation specification specifying te trophectoderm tyrosinated yap	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Difference) ?		apical blastocyst cdx2 compaction dampened derives erm gtpases hippo icm lats1 lineages nanog outer pard6b phosphorylating polarity polarization prkcz rho rock scrib segregation specification specifying te trophectoderm tyrosinated yap	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Intersection) ?