TBC1D15 and RAB5B

Number of citations of the paper that reports this interaction (PMID 16923123)
31

Data Source:
BioGRID (two hybrid)

		TBC1D15	RAB5B
Gene Name		TBC1 domain family, member 15	RAB5B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Extracellular Vesicular Exosome	Intracellular Endosome Early Endosome Plasma Membrane Membrane Endocytic Vesicle Early Endosome Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function	Rab GTPase Activator Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding
	Biological Process	Regulation Of Rab GTPase Activity Positive Regulation Of Rab GTPase Activity Regulation Of Cilium Assembly	Intracellular Protein Transport Endosome Organization Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Plasma Membrane To Endosome Transport
Pathways
Drugs
Diseases
GWAS			Polycystic ovary syndrome ( 22885925) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)
Protein-Protein Interactions		7 interactors: CALCOCO1 CEP63 FIS1 OPTN RAB5A RAB5B RAB5C	15 interactors: APOA5 CDK1 CHM EEA1 RAB7A RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC
Entrez ID		64786	5869
HPRD ID		15470	01544
Ensembl ID		ENSG00000121749	ENSG00000111540
Uniprot IDs		Q8TC07	P61020
PDB IDs			2HEI
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Rab Protein Signal Transduction Plasma Membrane To Endosome Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Regulation Of Endocytosis Establishment Of Protein Localization Intracellular Transport Endosomal Transport Ras Protein Signal Transduction Signal Transduction Signaling Cell Communication Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Cellular Response To Stimulus Cellular Localization Vesicle-mediated Transport G2/M Transition Of Mitotic Cell Cycle Small GTPase Mediated Signal Transduction Response To Stimulus Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Autophagy Negative Regulation Of Receptor Recycling Regulation Of Cellular Component Organization Golgi Ribbon Formation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Mitochondrial Fission Mitochondrial Fragmentation Involved In Apoptotic Process Wnt Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Peroxisome Fission Centriole Replication Regulation Of Mitochondrial Fission Calcium-mediated Signaling Using Intracellular Calcium Source Establishment Of Protein Localization To Organelle Mitochondrial Calcium Ion Homeostasis Mitochondrial Fusion Transport Early Endosome To Late Endosome Transport Centriole Assembly Protein Targeting Endomembrane System Organization Protein Targeting To Golgi	Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Vesicle-mediated Transport Endocytosis Regulation Of Catalytic Activity Positive Regulation Of Ras GTPase Activity Endosomal Transport Regulation Of Ras GTPase Activity Organelle Fusion Regulation Of Ras Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Transport Early Endosome To Late Endosome Transport Membrane Organization Regulation Of Signaling Cellular Localization Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Vesicle Fusion Protein Localization Regulation Of Signal Transduction Establishment Of Localization In Cell Synaptic Vesicle To Endosome Fusion Pronuclear Fusion Epidermal Growth Factor Catabolic Process Retrograde Transport, Endosome To Golgi Nuclear Envelope Organization Organ Regeneration Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Intracellular Transport Nuclear Matrix Organization Negative Regulation Of Synaptic Plasticity Nuclear Matrix Anchoring At Nuclear Membrane Nucleus Organization Phagosome-lysosome Fusion Nuclear Migration Along Microfilament Regulation Of Metabolic Process Membrane Fusion Phagosome Acidification Protein Localization To Organelle Regulation Of Schwann Cell Differentiation Protein Geranylgeranylation Protein To Membrane Docking
Tagcloud ?		abuse causally cd133 cd49f chemoresistance demonstration deprivation ectopically elusive hcv heightens igf2bp3 initiating linking nanog ns5a numb nutrient obligatory oncoprotein predisposes renewal reprogramming synergism synergistically tics tlr4 tumorigenic yap1
Tagcloud (Difference) ?		abuse causally cd133 cd49f chemoresistance demonstration deprivation ectopically elusive hcv heightens igf2bp3 initiating linking nanog ns5a numb nutrient obligatory oncoprotein predisposes renewal reprogramming synergism synergistically tics tlr4 tumorigenic yap1
Tagcloud (Intersection) ?