RAB5B and TFRC

Number of citations of the paper that reports this interaction (PMID 7789520)
36

Data Source:
HPRD (in vivo)

		RAB5B	TFRC
Gene Name		RAB5B, member RAS oncogene family	transferrin receptor
Image
Gene Ontology Annotations	Cellular Component	Intracellular Endosome Early Endosome Plasma Membrane Membrane Endocytic Vesicle Early Endosome Membrane Melanosome Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Endosome Plasma Membrane Integral Component Of Plasma Membrane Coated Pit External Side Of Plasma Membrane Cell Surface Membrane Cytoplasmic Membrane-bounded Vesicle Vesicle Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding	Double-stranded RNA Binding Transferrin Receptor Activity Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Intracellular Protein Transport Endosome Organization Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Plasma Membrane To Endosome Transport	Regulation Of Cell Growth Cellular Iron Ion Homeostasis Receptor-mediated Endocytosis Viral Process Osteoclast Differentiation Transferrin Transport Cellular Response To Drug Regulation Of Cell Proliferation Positive Regulation Of Bone Resorption Transmembrane Transport Iron Ion Import
Pathways			Iron uptake and transport Golgi Associated Vesicle Biogenesis Transferrin endocytosis and recycling trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 22885925) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)	Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 20139978 19862010) Pancreatic cancer ( 22158540) Red blood cell traits ( 23222517)
Protein-Protein Interactions		15 interactors: APOA5 CDK1 CHM EEA1 RAB7A RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC	11 interactors: ACAP1 B4GALT1 CD247 CD4 GABARAP HFE RAB5B RAB8A RANBP9 SGTA TF
Entrez ID		5869	7037
HPRD ID		01544	01812
Ensembl ID		ENSG00000111540	ENSG00000072274
Uniprot IDs		P61020	A8K6Q8 P02786
PDB IDs		2HEI	1CX8 1DE4 1SUV 2NSU 3KAS 3S9L 3S9M 3S9N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Vesicle-mediated Transport Endocytosis Regulation Of Catalytic Activity Positive Regulation Of Ras GTPase Activity Endosomal Transport Regulation Of Ras GTPase Activity Organelle Fusion Regulation Of Ras Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Transport Early Endosome To Late Endosome Transport Membrane Organization Regulation Of Signaling Cellular Localization Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Vesicle Fusion Protein Localization Regulation Of Signal Transduction Establishment Of Localization In Cell Synaptic Vesicle To Endosome Fusion Pronuclear Fusion Epidermal Growth Factor Catabolic Process Retrograde Transport, Endosome To Golgi Nuclear Envelope Organization Organ Regeneration Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Intracellular Transport Nuclear Matrix Organization Negative Regulation Of Synaptic Plasticity Nuclear Matrix Anchoring At Nuclear Membrane Nucleus Organization Phagosome-lysosome Fusion Nuclear Migration Along Microfilament Regulation Of Metabolic Process Membrane Fusion Phagosome Acidification Protein Localization To Organelle Regulation Of Schwann Cell Differentiation Protein Geranylgeranylation Protein To Membrane Docking	Protein Localization Protein Transport Establishment Of Protein Localization Regulation Of Defense Response To Virus By Virus Cellular Protein Localization Cellular Localization Transport Rab Protein Signal Transduction Cellular Response To Iron Ion Starvation Induction By Virus Of Host Cell-cell Fusion Protein Palmitoleylation T Cell Costimulation Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Iron Ion Transport Regulation Of Defense Response To Virus Cellular Iron Ion Homeostasis T Cell Receptor Signaling Pathway Establishment Of Localization In Cell Iron Ion Homeostasis Lactose Biosynthetic Process Golgi Vesicle Fusion To Target Membrane Membrane Fusion Viral Process Immune System Process Response To Stimulus Antigen Receptor-mediated Signaling Pathway Cellular Response To Starvation Transition Metal Ion Homeostasis Response To Stress Regulation Of Exocytosis Disaccharide Metabolic Process Positive Regulation Of Immune Response Cellular Response To Nutrient Levels Response To Starvation Iron Ion Import Into Cell Vesicle-mediated Transport Penetration Of Zona Pellucida Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Plasma Membrane To Endosome Transport Intracellular Transport Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Positive Regulation Of T Cell Activation Cellular Response To Extracellular Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Ras Protein Signal Transduction Multicellular Organismal Homeostasis Regulation Of Acrosome Reaction Positive Regulation Of Cell-cell Adhesion Cell Communication
Tagcloud ?			actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately stmn1 taqman top2a tubb3 tyms vegfr2
Tagcloud (Difference) ?			actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately stmn1 taqman top2a tubb3 tyms vegfr2
Tagcloud (Intersection) ?