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RAB5B and RIN1
Number of citations of the paper that reports this interaction (PMID
11703925
)
76
Data Source:
HPRD
(two hybrid, in vitro)
RAB5B
RIN1
Gene Name
RAB5B, member RAS oncogene family
Ras and Rab interactor 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Endosome
Early Endosome
Plasma Membrane
Membrane
Endocytic Vesicle
Early Endosome Membrane
Melanosome
Extracellular Vesicular Exosome
Cytoplasm
Cytoskeleton
Plasma Membrane
Dendrite
Neuronal Cell Body
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
GTP-dependent Protein Binding
GTPase Activator Activity
Protein Binding
Ras GTPase Binding
Biological Process
Intracellular Protein Transport
Endosome Organization
Antigen Processing And Presentation
Regulation Of Endocytosis
Rab Protein Signal Transduction
Plasma Membrane To Endosome Transport
Endocytosis
Signal Transduction
Memory
Associative Learning
Negative Regulation Of Synaptic Plasticity
Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Polycystic ovary syndrome (
22885925
)
Type 1 diabetes (
18198356
)
Vitiligo (
22951725
)
Bipolar disorder (
21926972
)
Protein-Protein Interactions
15 interactors:
APOA5
CDK1
CHM
EEA1
RAB7A
RABAC1
REEP5
RIN1
RIN2
RIN3
SGSM3
SUN2
TBC1D15
TBC1D17
TFRC
15 interactors:
ABL1
ABL2
CALCOCO2
ERBB2
ERBB3
HRAS
LZTS2
MLLT4
RAB5A
RAB5B
RALGDS
RRAS2
YWHAB
YWHAE
YWHAZ
Entrez ID
5869
9610
HPRD ID
01544
05813
Ensembl ID
ENSG00000111540
ENSG00000174791
Uniprot IDs
P61020
Q13671
PDB IDs
2HEI
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Rab GTPase Activity
Regulation Of Rab GTPase Activity
Regulation Of Rab Protein Signal Transduction
Positive Regulation Of Catalytic Activity
Positive Regulation Of Hydrolase Activity
Positive Regulation Of GTPase Activity
Regulation Of GTPase Activity
Vesicle-mediated Transport
Endocytosis
Regulation Of Catalytic Activity
Positive Regulation Of Ras GTPase Activity
Endosomal Transport
Regulation Of Ras GTPase Activity
Organelle Fusion
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Metabolic Process
Regulation Of Small GTPase Mediated Signal Transduction
Transport
Early Endosome To Late Endosome Transport
Membrane Organization
Regulation Of Signaling
Cellular Localization
Ras Protein Signal Transduction
Regulation Of Intracellular Signal Transduction
Small GTPase Mediated Signal Transduction
Vesicle Fusion
Protein Localization
Regulation Of Signal Transduction
Establishment Of Localization In Cell
Synaptic Vesicle To Endosome Fusion
Pronuclear Fusion
Epidermal Growth Factor Catabolic Process
Retrograde Transport, Endosome To Golgi
Nuclear Envelope Organization
Organ Regeneration
Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling
Intracellular Transport
Nuclear Matrix Organization
Negative Regulation Of Synaptic Plasticity
Nuclear Matrix Anchoring At Nuclear Membrane
Nucleus Organization
Phagosome-lysosome Fusion
Nuclear Migration Along Microfilament
Regulation Of Metabolic Process
Membrane Fusion
Phagosome Acidification
Protein Localization To Organelle
Regulation Of Schwann Cell Differentiation
Protein Geranylgeranylation
Protein To Membrane Docking
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Intracellular Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Ras Protein Signal Transduction
Neurotrophin Signaling Pathway
Regulation Of Signaling
Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Signaling
Cell Communication
Apoptotic Signaling Pathway
Regulation Of Signal Transduction
Intrinsic Apoptotic Signaling Pathway
Response To Stimulus
Cellular Response To Stimulus
Innate Immune Response
Positive Regulation Of Signal Transduction
Immune Response
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Defense Response
Regulation Of Cellular Component Organization
Fc Receptor Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cellular Response To Growth Factor Stimulus
Wound Healing
Response To Growth Factor
Small GTPase Mediated Signal Transduction
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Catalytic Activity
Immune System Process
Regulation Of Cell Death
Regulation Of Cellular Localization
Regulation Of Actin Cytoskeleton Reorganization
Positive Regulation Of Interferon-gamma Secretion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Response To Wounding
Regulation Of Catalytic Activity
Axon Guidance
Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Transport
Regulation Of Intracellular Signal Transduction
Glial Cell Differentiation
Regulation Of Endocytosis
Response To Organic Substance
Negative Regulation Of Protein Dephosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of Protein Localization
Tagcloud
?
abcc12
braf
dabrafenib
deregulated
deserve
detoxification
discover
exploratory
highlighted
invasiveness
klf17
melanoma
mtefd1
nqo1
peaks
rbm10
responder
responders
seldi
silico
slain1
strongest
surrogates
tox3
tspo2
v600
vemurafenib
z
zbtb44
Tagcloud (Difference)
?
abcc12
braf
dabrafenib
deregulated
deserve
detoxification
discover
exploratory
highlighted
invasiveness
klf17
melanoma
mtefd1
nqo1
peaks
rbm10
responder
responders
seldi
silico
slain1
strongest
surrogates
tox3
tspo2
v600
vemurafenib
z
zbtb44
Tagcloud (Intersection)
?