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RAB5B
Description
RAB5B, member RAS oncogene family
Image
GO Annotations
Cellular Component
Endosome
Early Endosome
Plasma Membrane
Endomembrane System
Membrane
Endocytic Vesicle
Secretory Granule Membrane
Synaptic Vesicle Membrane
Early Endosome Membrane
Melanosome
Extracellular Exosome
Molecular Function
Nucleotide Binding
GTPase Activity
G Protein Activity
Protein Binding
GTP Binding
Hydrolase Activity
GDP Binding
GTP-dependent Protein Binding
Metal Ion Binding
Biological Process
Intracellular Protein Transport
Endocytosis
Endosome Organization
Protein Transport
Endosomal Transport
Antigen Processing And Presentation
Regulation Of Endocytosis
Plasma Membrane To Endosome Transport
Pathways
Neutrophil degranulation
TBC/RABGAPs
Clathrin-mediated endocytosis
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Respiratory syncytial virus (RSV) attachment and entry
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever and/or eczema) (age of onset) (
32603359
)
Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) (
32603359
)
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Anorexia nervosa (
28494655
)
Aspartate aminotransferase levels (
33547301
)
Asthma (
31959851
31619474
30929738
)
Asthma (adult onset) (
31036433
)
Asthma (childhood onset) (
30929738
31036433
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Brain morphology (MOSTest) (
32665545
)
Cognitive function (
25644384
)
FEV1 (
30804560
)
Gastroesophageal reflux disease (
31527586
)
HDL cholesterol levels (
32203549
)
High density lipoprotein cholesterol levels (
31928498
)
Lung function (FEV1) (
30061609
)
Lung function (FEV1/FVC) (
30804560
)
Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) (
31015401
)
Polycystic ovary syndrome (
30566500
22885925
)
Refractive error (
32231278
)
Sum eosinophil basophil counts (
27863252
)
Type 1 diabetes (
18198356
)
Vitiligo (
22951725
)
Novel Interacting Genes
1 novel interacting genes:
PRIM1
Interacting Genes
19 interacting genes:
APOA5
CDK1
CHM
EEA1
FHIP1B
GLP1R
HUNK
PIK3CB
RABAC1
REEP5
RIN1
RIN2
RIN3
SGSM3
SNCA
SUN2
TBC1D15
TBC1D17
TFRC
Entrez ID
5869
HPRD ID
01544
Ensembl ID
ENSG00000111540
Uniprot IDs
P61020
PDB IDs
2HEI
Enriched GO Terms of Interacting Partners
?
Vesicle-mediated Transport
GTPase Activator Activity
Endocytosis
Import Into Cell
Response To Copper Ion
Small GTPase Binding
Hsp70 Protein Binding
Regulation Of Endocytosis
Endocytic Vesicle
Endosome
Establishment Of Localization In Cell
Endosomal Transport
Regulation Of Cilium Assembly
Intracellular Transport
Regulation Of Vesicle-mediated Transport
Early Endosome To Late Endosome Transport
Regulation Of Receptor-mediated Endocytosis
Intracellular Signal Transduction
Early Endosome
Recycling Endosome
Response To Iron Ion
Regulation Of Cellular Component Organization
Pronuclear Fusion
Cellular Localization
Glucagon-like Peptide 1 Receptor Activity
Ribonucleotide Binding
Response To Desipramine
Negative Regulation Of Norepinephrine Uptake
Phospholipase D Inhibitor Activity
Positive Regulation Of SNARE Complex Assembly
Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Mast Cell Chemotaxis
Regulation Of Transport
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