RAB5B and SUN2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RAB5B	SUN2
Gene Name		RAB5B, member RAS oncogene family	Sad1 and UNC84 domain containing 2
Image
Gene Ontology Annotations	Cellular Component	Intracellular Endosome Early Endosome Plasma Membrane Membrane Endocytic Vesicle Early Endosome Membrane Melanosome Extracellular Vesicular Exosome	Nuclear Chromosome, Telomeric Region Condensed Nuclear Chromosome Nuclear Envelope Integral Component Of Nuclear Inner Membrane Endosome Membrane Nuclear Membrane LINC Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Endosome Organization Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Plasma Membrane To Endosome Transport	Nuclear Envelope Organization Mitotic Spindle Organization Nuclear Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Centrosome Localization Cytoskeletal Anchoring At Nuclear Membrane Nuclear Matrix Anchoring At Nuclear Membrane
Pathways			Meiotic synapsis
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 22885925) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)
Protein-Protein Interactions		15 interactors: APOA5 CDK1 CHM EEA1 RAB7A RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC	5 interactors: HGS NRM RAB5A RAB5B RPS20
Entrez ID		5869	25777
HPRD ID		01544	15611
Ensembl ID		ENSG00000111540	ENSG00000100242
Uniprot IDs		P61020	B4E2A6 J3KQE0 Q9UH99
PDB IDs		2HEI	3UNP 4DXR 4DXS 4DXT 4FI9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Vesicle-mediated Transport Endocytosis Regulation Of Catalytic Activity Positive Regulation Of Ras GTPase Activity Endosomal Transport Regulation Of Ras GTPase Activity Organelle Fusion Regulation Of Ras Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Transport Early Endosome To Late Endosome Transport Membrane Organization Regulation Of Signaling Cellular Localization Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Vesicle Fusion Protein Localization Regulation Of Signal Transduction Establishment Of Localization In Cell Synaptic Vesicle To Endosome Fusion Pronuclear Fusion Epidermal Growth Factor Catabolic Process Retrograde Transport, Endosome To Golgi Nuclear Envelope Organization Organ Regeneration Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Intracellular Transport Nuclear Matrix Organization Negative Regulation Of Synaptic Plasticity Nuclear Matrix Anchoring At Nuclear Membrane Nucleus Organization Phagosome-lysosome Fusion Nuclear Migration Along Microfilament Regulation Of Metabolic Process Membrane Fusion Phagosome Acidification Protein Localization To Organelle Regulation Of Schwann Cell Differentiation Protein Geranylgeranylation Protein To Membrane Docking	Cytoplasmic Transport Endosomal Transport Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Cellular Protein Localization Rab Protein Signal Transduction Protein Transport Positive Regulation Of Exocytosis Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Regulation Of Exocytosis Cellular Localization Regulation Of Endocytosis Regulation Of Endosome Size Receptor Internalization Involved In Canonical Wnt Signaling Pathway Ras Protein Signal Transduction Plasma Membrane To Endosome Transport Positive Regulation Of Secretion Establishment Of Protein Localization To Organelle Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Localization To Membrane Protein Targeting To Lysosome Protein Localization To Lysosome Protein Targeting Cytoplasmic Translation Membrane Invagination Early Endosome To Late Endosome Transport Protein Localization To Organelle Protein Targeting To Vacuole Negative Regulation Of JAK-STAT Cascade Establishment Of Protein Localization To Vacuole Positive Regulation Of Smooth Muscle Cell Migration Endosome To Lysosome Transport Endosome Organization Small GTPase Mediated Signal Transduction Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Secretion Regulation Of Synaptic Vesicle Exocytosis Synaptic Vesicle Recycling Transport Regulation Of Synaptic Vesicle Transport Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Transport Receptor Internalization Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Filopodium Assembly
Tagcloud ?			arrangement c2c12 cardiomyopathy centrosomal connects dreifuss dystrophy edmd emery exemplified gross identifiable linc microtubule modifier muscular myonuclear myopathies myotubes ne nucleation pericentrin phenotypically positioning rearward recapitulated repositioning segregating sun1
Tagcloud (Difference) ?			arrangement c2c12 cardiomyopathy centrosomal connects dreifuss dystrophy edmd emery exemplified gross identifiable linc microtubule modifier muscular myonuclear myopathies myotubes ne nucleation pericentrin phenotypically positioning rearward recapitulated repositioning segregating sun1
Tagcloud (Intersection) ?