TBC1D15 and RAB5C

Number of citations of the paper that reports this interaction (PMID 16923123)
31

Data Source:
BioGRID (two hybrid)

		TBC1D15	RAB5C
Gene Name		TBC1 domain family, member 15	RAB5C, member RAS oncogene family
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Extracellular Vesicular Exosome	Lysosomal Membrane Early Endosome Lipid Particle Plasma Membrane Endocytic Vesicle Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Rab GTPase Activator Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Regulation Of Rab GTPase Activity Positive Regulation Of Rab GTPase Activity Regulation Of Cilium Assembly	Intracellular Protein Transport Regulation Of Endocytosis Rab Protein Signal Transduction Plasma Membrane To Endosome Transport
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CALCOCO1 CEP63 FIS1 OPTN RAB5A RAB5B RAB5C	10 interactors: APP APPL2 EEA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17
Entrez ID		64786	5878
HPRD ID		15470	04947
Ensembl ID		ENSG00000121749	ENSG00000108774
Uniprot IDs		Q8TC07	P51148
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Rab Protein Signal Transduction Plasma Membrane To Endosome Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Regulation Of Endocytosis Establishment Of Protein Localization Intracellular Transport Endosomal Transport Ras Protein Signal Transduction Signal Transduction Signaling Cell Communication Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Cellular Response To Stimulus Cellular Localization Vesicle-mediated Transport G2/M Transition Of Mitotic Cell Cycle Small GTPase Mediated Signal Transduction Response To Stimulus Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Autophagy Negative Regulation Of Receptor Recycling Regulation Of Cellular Component Organization Golgi Ribbon Formation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Mitochondrial Fission Mitochondrial Fragmentation Involved In Apoptotic Process Wnt Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Peroxisome Fission Centriole Replication Regulation Of Mitochondrial Fission Calcium-mediated Signaling Using Intracellular Calcium Source Establishment Of Protein Localization To Organelle Mitochondrial Calcium Ion Homeostasis Mitochondrial Fusion Transport Early Endosome To Late Endosome Transport Centriole Assembly Protein Targeting Endomembrane System Organization Protein Targeting To Golgi	Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Ras GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Ras GTPase Activity Regulation Of Catalytic Activity Regulation Of Ras Protein Signal Transduction Vesicle-mediated Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Catalytic Activity Regulation Of GTPase Activity Regulation Of Signal Transduction Regulation Of Signaling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Endosomal Transport Endocytosis Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Regulation Of Intracellular Signal Transduction Mating Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Regulation Of ERBB Signaling Pathway Synaptic Vesicle To Endosome Fusion Feeding Behavior Cholesterol Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of Receptor Activity Sterol Metabolic Process Neuromuscular Process Intracellular Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Transition Metal Ion Homeostasis Transport Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition Plasma Membrane To Endosome Transport Locomotory Behavior Establishment Of Localization In Cell
Tagcloud ?		abuse causally cd133 cd49f chemoresistance demonstration deprivation ectopically elusive hcv heightens igf2bp3 initiating linking nanog ns5a numb nutrient obligatory oncoprotein predisposes renewal reprogramming synergism synergistically tics tlr4 tumorigenic yap1	cdc42 compartment coordinately cytomegalovirus ectopic encode golgi hcmv herpesviruses infectious micrornas mirna mirnas mirs morphogenesis noninfectious rab11a reorganization resemble secretory sirnas snap23 stacks ul112 uncovered us5 vac vamp3 virion
Tagcloud (Difference) ?		abuse causally cd133 cd49f chemoresistance demonstration deprivation ectopically elusive hcv heightens igf2bp3 initiating linking nanog ns5a numb nutrient obligatory oncoprotein predisposes renewal reprogramming synergism synergistically tics tlr4 tumorigenic yap1	cdc42 compartment coordinately cytomegalovirus ectopic encode golgi hcmv herpesviruses infectious micrornas mirna mirnas mirs morphogenesis noninfectious rab11a reorganization resemble secretory sirnas snap23 stacks ul112 uncovered us5 vac vamp3 virion
Tagcloud (Intersection) ?