MTMR14 and TP53BP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MTMR14	TP53BP2
Gene Name		myotubularin related protein 14	tumor protein p53 binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytosol Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Tyrosine Phosphatase Activity	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Identical Protein Binding NF-kappaB Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Small Molecule Metabolic Process	Cell Cycle Signal Transduction Central Nervous System Development Heart Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Signal Transduction Response To Ionizing Radiation Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APP TP53BP2	58 interactors: APP ATPAF2 ATXN7 BAIAP2 BCL2 BCL2L1 CCDC92 CSNK2B CWF19L2 DCUN1D1 EEF1A1 GRB2 HIST1H2BC HNRNPUL1 KIF5A LMO4 MAGI1 MAPK8IP2 MRPL20 MTMR14 NAE1 NDC80 NUTM1 OTUB2 PLEKHN1 PLK1 POLR2L PPHLN1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PTN RELA SIAH1 SIAH2 SSX2IP SUMO2 SUMO3 TANK TBC1D22B TCL1A TP53 TRAF4 TXLNA UBASH3A UNC119 USP4 UTP14A WWP1 WWP2 YAP1 YES1 YWHAG YWHAQ ZGPAT ZNF26
Entrez ID		64419	7159
HPRD ID		08654	11803
Ensembl ID		ENSG00000163719	ENSG00000143514
Uniprot IDs		Q8NCE2 Q8WYY9	Q13625
PDB IDs			1YCS 2UWQ 4A63
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Response To Radiation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Regulation Of Cell Cycle Apoptotic Process Central Nervous System Development Copper Ion Homeostasis Suckling Behavior Programmed Cell Death Cell Death Death Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Abiotic Stimulus Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth	Neuron Death Neuron Apoptotic Process Response To Radiation Regulation Of Signal Transduction Regulation Of Signaling Response To External Stimulus Negative Regulation Of Signal Transduction Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Signaling Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Apoptotic Signaling Pathway Cell Part Morphogenesis Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Phosphorylation Response To Light Stimulus Protein Modification By Small Protein Conjugation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Cycle Neuron Projection Morphogenesis Regulation Of Mitochondrion Organization Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cell Projection Morphogenesis Axonogenesis Cellular Protein Modification Process Positive Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Cell Morphogenesis Regulation Of Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Regulation Of Cellular Protein Metabolic Process Response To Gamma Radiation Axon Development Regulation Of Extrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Generation Of Neurons Nervous System Development Cellular Response To Ionizing Radiation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Innate Immune Response Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Neuron Projection Development Neurogenesis Anatomical Structure Morphogenesis
Tagcloud ?		3p anomalies arm camk1 congenital creld1 define deleted deletion deletions features give handicap interstitial involve kb lengths mb overlap presents prove respect rise seizures srgap3 syndrome tada3 terminus typical	adenovirus angiotensin apoptosis array at2r bag3 bmp6 bmp7 bnipi cytokine downregulation du145 gadd45a hrk il6 il8 mapk microrna next numerous p44 pc r2 silence sirnas tnfsf10 trail transduced utilized
Tagcloud (Difference) ?		3p anomalies arm camk1 congenital creld1 define deleted deletion deletions features give handicap interstitial involve kb lengths mb overlap presents prove respect rise seizures srgap3 syndrome tada3 terminus typical	adenovirus angiotensin apoptosis array at2r bag3 bmp6 bmp7 bnipi cytokine downregulation du145 gadd45a hrk il6 il8 mapk microrna next numerous p44 pc r2 silence sirnas tnfsf10 trail transduced utilized
Tagcloud (Intersection) ?