FXR2 and POM121

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FXR2	POM121
Gene Name		fragile X mental retardation, autosomal homolog 2	POM121 transmembrane nucleoporin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Polysome Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Membrane Nuclear Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Translation	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS		IgM levels ( 23118916) Sex hormone-binding globulin levels ( 22675492)	Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		90 interactors: AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2D CBS CCDC33 CCDC85B CDKL3 CEP44 CEP55 COIL CYFIP1 CYFIP2 DPPA2 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 HMBOX1 HNRNPC KCNRG KCTD4 KIAA1217 KIF1A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDN NECAB2 NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PIM1 POM121 PRAM1 PSME3 PTS RABAC1 RALYL RBBP8 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SRPK2 SSSCA1 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF451 ZSCAN1	21 interactors: AGR2 AP2B1 APC ATXN1 BRCA1 CEP55 CEP76 CLDN3 COL4A3BP FXR2 GFAP GOLGA2 GYG1 HOMER3 LPXN NFKBIA PAXIP1 RBPMS TEX11 TRIM23 TRIP6
Entrez ID		9513	9883
HPRD ID		05629	11448
Ensembl ID		ENSG00000129245	ENSG00000196313
Uniprot IDs		P51116	Q96HA1
PDB IDs		3H8Z
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Negative Regulation Of Centriole Replication Macromolecule Biosynthetic Process Developmental Cell Growth Protein Homooligomerization Tetrahydrobiopterin Biosynthetic Process Pteridine-containing Compound Biosynthetic Process Endoplasmic Reticulum Tubular Network Organization Cellular Macromolecule Biosynthetic Process Protein Autoubiquitination Protein Oligomerization Histone Acetylation Vesicle-mediated Transport Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Regulation Of Centriole Replication Histone H4 Acetylation Internal Protein Amino Acid Acetylation Pteridine-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Negative Regulation Of Gene Expression Protein Acetylation DNA Recombination Histone H2A Acetylation Cellular Metabolic Process Neuron Projection Extension Negative Regulation Of Centrosome Duplication Cell Growth Negative Regulation Of Cell Growth Histone Modification	Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Negative Regulation Of Signal Transduction Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Signaling Regulation Of Microtubule-based Process Regulation Of Protein Import Into Nucleus Positive Regulation Of Histone Methylation Mitotic Cytokinesis Regulation Of NF-kappaB Import Into Nucleus Regulation Of Signaling Regulation Of Protein Localization To Nucleus Regulation Of Centrosome Duplication Regulation Of Chromosome Organization Regulation Of Histone Acetylation Cell Cycle Regulation Of Nucleocytoplasmic Transport Regulation Of Centrosome Cycle Signaling Regulation Of Histone Methylation Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Schwann Cell Proliferation Cell Communication DNA Recombination Cellular Response To Stress Regulation Of Intracellular Protein Transport Regulation Of Signal Transduction Cell Cycle Process Positive Regulation Of Histone Modification Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Mucus Secretion Positive Regulation Of Histone H3-K9 Acetylation ER To Golgi Ceramide Transport Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Signal Transduction Response To Abiotic Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Chromosome Organization Lung Goblet Cell Differentiation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Transcription Factor Import Into Nucleus Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Import Into Nucleus
Tagcloud ?		17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned	antagonize brd1 brings childhood chimeric comprise dach1 encoding fluorescence frame fusion fusions hipk1 hybridization identification implicated least leukemia lymphoblastic master occur partner pax5 precursor rearrangements regulator situ transduction tumorigenesis
Tagcloud (Difference) ?		17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned	antagonize brd1 brings childhood chimeric comprise dach1 encoding fluorescence frame fusion fusions hipk1 hybridization identification implicated least leukemia lymphoblastic master occur partner pax5 precursor rearrangements regulator situ transduction tumorigenesis
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