FXR2 and BAZ2B

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		FXR2	BAZ2B
Name		FMR1 autosomal homolog 2	bromodomain adjacent to zinc finger domain 2B
Structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Cytoplasmic Ribonucleoprotein Granule Neuron Projection Synapse Presynapse Postsynapse	Chromatin Nucleus
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Translation Dentate Gyrus Development Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Long-term Neuronal Synaptic Plasticity Animal Organ Development MRNA Transport MRNA Destabilization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II
GWAS		Atrial fibrillation ( 30061737 ) Brain morphology (MOSTest) ( 32665545 ) IgM levels ( 23118916 ) Monocyte count ( 32888494 ) Refractive error ( 32231278 ) Sex hormone-binding globulin levels ( 22675492 )	Femur bone mineral density x serum urate levels interaction ( 34046847 ) Ferritin levels ( 33491795 ) Major depressive episode treated with electroconvulsive therapy ( 33483693 ) Monocyte count ( 32888494 ) Neutrophil percentage of white cells ( 32888494 ) Night sleep phenotypes ( 27126917 ) Proportion of activated microglia (inferior temporal cortex) ( 30679421 ) Refractive error ( 32231278 ) Sudden cardiac arrest ( 21738491 ) Tourette syndrome ( 30818990 )
Interacting Genes		191 interacting genes: AKAP9 AMOTL2 AP1M1 AP2M1 ARHGEF7 ARL6IP1 ATN1 AXIN1 AXIN2 BAZ2B BCKDK BCL11A BLK BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2B CAMK2G CAPRIN1 CBS CCAR2 CCDC33 CCDC85B CCDC92 CCN3 CCR4 CDKL3 CEP44 CEP55 CHRD COIL COMT CSNK2B CWF19L2 CYFIP1 CYFIP2 DCTN2 DCTPP1 DDX17 DEAF1 DGKD DMRTB1 DNM2 DPPA2 DYNLT1 ECH1 ECHS1 EDC4 EGFL7 EIF4G1 EVL EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GFAP GKAP1 GOLGA2 GPSM1 GPSM2 GRIP1 GTSE1 HIVEP1 HMBOX1 HNRNPC HNRNPM HNRNPR HOMER3 HSPB1 IGFN1 IMPDH2 INPP5J KCNRG KCTD4 KHDRBS1 KIAA1217 KIF1A KIF2A KIF7 KRT18 KRT20 KXD1 L3MBTL1 L3MBTL3 LASP1 LCMT1 LCP2 LDOC1 MAGED1 MAPKBP1 MAPRE3 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MPP1 MRPL43 MSANTD3 MVP MYH10 NASP NCK2 NDEL1 NDN NECAB2 NEXN NIF3L1 NKD2 NME1 NME3 NONO NT5C2 PAF1 PAICS PCBD1 PCM1 PDE9A PHC1P1 PHC2 PHLDB1 PICK1 PIM1 PKM PNMA1 POM121 PPP1R12C PRAM1 PRC1 PRPF6 PSME1 PSME3 PTS PYCR2 PYCR3 RABAC1 RAD54L2 RAI2 RALYL RBBP8 RBM14 RBM45 RBMX RBPMS RPIA RPS2 RTN3 RTN4 SCEL SCMH1 SF3B2 SFPQ SNAP23 SPRY1 SPRY2 SRPK2 SYT6 SYTL4 TBC1D22B TFCP2 THAP1 TLE5 TNFAIP1 TNIP2 TNNT1 TRAF2 TRIM23 TRIM29 TRIM3 TRIM37 TRIOBP TSC22D4 TUT4 USP39 VIM WDR59 WEE2-AS1 YES1 ZBTB22 ZBTB8A ZMAT2 ZMYND8 ZNF232 ZNF451 ZNRD2 ZSCAN1	20 interacting genes: APIP BCL2L13 BIVM CEP70 CTBP2 FOXP1 FXR2 GOLGA2 HMBOX1 HSF2BP PRNP RASGEF1B RNF10 SEPTIN2 STAC3 TFIP11 TRAF2 TRIM23 ZBTB14 ZBTB8A
Entrez ID		9513	29994
HPRD ID		05629	09295
Ensembl ID		ENSG00000129245	ENSG00000123636
Uniprot IDs		P51116	Q9UIF8
PDB IDs		3H8Z	2E7O 3G0L 3Q2F 4CUP 4CUQ 4CUR 4CUS 4CUT 4CUU 4IR3 4IR4 4IR5 4IR6 4NR9 4NRA 4NRB 4NRC 4QC1 4QC3 4QF3 4RVR 4XUA 4XUB 5CQ3 5CQ4 5CQ5 5CQ6 5CQ7 5CQ8 5CQA 5CU8 5CUA 5CUB 5CUC 5CUD 5CUE 5CUG 5DYU 5DYX 5E73 5E74 5E9I 5E9K 5E9L 5E9M 5E9Y 5L8T 5L8U 5L96 5L97 5L98 5L99 5MGE 5MGF 5MGG 5OR9 5ORB 5PB7 5PB8 5PB9 5PBA 5PBB 5PBC 5PBD 5PBE 5PBF 5PBG 5PBH 5PBI 5PBJ 5PBK 5PBL 5PBM 5PBN 5PBO 5PBP 5PBQ 5PBR 5PBS 5PBT 5PBU 5PBV 5PBW 5PBX 5PBY 5PBZ 5PC0 5PC1 5PC2 5PC3 5PC4 5PC5 5PC6 5PC7 5PC8 5PC9 5PCA 5PCB 5PCC 5PCD 5PCE 5PCF 5PCG 5PCH 5PCI 5PCJ 5PCK 5PCL 5PCM 5PCN 5PCO 5PCP 5PCQ 5PCR 5PCS 5PCT 5PCU 5PCV 5PCW 5PCX 5PCZ 5PD0 5PD1 5PD2 5PD3 5PD4 5PD5 5PD6 5PD7 5PD8 5PD9 5PDA 5PDB 5PDC 5PDD 5PDE 5PDF 5PDG 5PDH 5PDI 5PDJ 5PDK 5PDL 5PDM 5PDN 5PDO 5PDP 5PDQ 5PDR 5PDS 5PDT 5PDU 5PDV 5PDW 5PDX 5PDY 5PDZ 5PE0 5PE1 5PE2 5PE3 5PE4 5PE5 5PE6 5PE7 5PE8 5PE9 5PEA 5PEB 5PEC 5PED 5PEE 5PEF 5PEG 5PEH 5PEI 5PEJ 5PEK 5PEL 5PEM 5PEN 5PEO 5PEQ 5PER 5PES 5PET 5PEU 5PEV 5PEW 5PEX 5PEY 5PEZ 5PF0 5PF1 5PF2 5PF3 5PF4 5PF5 5PF6 5PF7 5PF8 5PF9 5PFA 5PFB 5PFC 5PFD 5PFE 5PFF 5PFG 5PFH 5PFI 5PFJ 5PFL 5PFM 5PFN 5PFO 5PFP 5PFQ 5PFR 5PFS 5PFT 5PFU 5PFV 5PFW 5PFX 5PFY 5PFZ 5PG0 5PG1 5PG2 5PG3 5PG4 5PG5 5PG6 5PG7 5PG8 5PG9 5PGA 5PGB 5PGC 5PGD 5PGE 5PGF 5PGG 5PGH 5PGI 5PGJ 5PGK 5PGL 5PGN 5PGO 5PGP 5PGQ 5PGR 5PGS 5PGT 6FGT 6FGU 6FH6 6FH7 6FHQ 6FI1 7Q42 7WIN
GO Terms Enriched among Interactors		Identical Protein Binding Protein Binding Cytoplasm Cytosol Cytoskeleton Negative Regulation Of RNA Metabolic Process Neuron Projection MRNA Metabolic Process MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing RNA Splicing, Via Transesterification Reactions Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Establishment Of Mitotic Spindle Orientation Paraspeckles Nucleoplasm Regulation Of RNA Metabolic Process Centrosome Regulation Of Neurotrophin TRK Receptor Signaling Pathway MRNA Binding Negative Regulation Of DNA-templated Transcription Establishment Of Mitotic Spindle Localization Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Component Organization Negative Regulation Of Macromolecule Metabolic Process Establishment Of Spindle Orientation Microtubule-based Process Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Nucleobase-containing Compound Metabolic Process Nucleolus Regulation Of MRNA Metabolic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Dendritic Spine Development RNA Binding Signaling Adaptor Activity Negative Regulation Of Metabolic Process Establishment Of Spindle Localization Negative Regulation Of Centriole Replication Intracellular Membraneless Organelle Establishment Of Organelle Localization Protein Domain Specific Binding Spindle Localization Regulation Of DNA-templated Transcription Regulation Of Cell Projection Organization Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Dendritic Spine Development Endoplasmic Reticulum Tubular Network Membrane Organization System Development	Identical Protein Binding