FXR2 and SYT6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FXR2	SYT6
Gene Name		fragile X mental retardation, autosomal homolog 2	synaptotagmin VI
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Polysome Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Cytosol Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Cell Junction Synaptic Vesicle Membrane Perinuclear Endoplasmic Reticulum
	Molecular Function	RNA Binding MRNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding	Transporter Activity Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Translation	Acrosomal Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		IgM levels ( 23118916) Sex hormone-binding globulin levels ( 22675492)	Breast cancer (prognosis) ( 23319801) Obesity-related traits ( 23251661)
Protein-Protein Interactions		90 interactors: AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2D CBS CCDC33 CCDC85B CDKL3 CEP44 CEP55 COIL CYFIP1 CYFIP2 DPPA2 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 HMBOX1 HNRNPC KCNRG KCTD4 KIAA1217 KIF1A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDN NECAB2 NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PIM1 POM121 PRAM1 PSME3 PTS RABAC1 RALYL RBBP8 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SRPK2 SSSCA1 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF451 ZSCAN1	15 interactors: APP BRCA1 DVL3 FXR2 GOLGA2 KCTD9 KRT40 MTUS2 NRXN1 PRKCB TNIP1 TRIM32 TSGA10 ZBTB43 ZBTB8A
Entrez ID		9513	148281
HPRD ID		05629	09654
Ensembl ID		ENSG00000129245	ENSG00000134207
Uniprot IDs		P51116	I6L9C3 Q5T7P8
PDB IDs		3H8Z
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Negative Regulation Of Centriole Replication Macromolecule Biosynthetic Process Developmental Cell Growth Protein Homooligomerization Tetrahydrobiopterin Biosynthetic Process Pteridine-containing Compound Biosynthetic Process Endoplasmic Reticulum Tubular Network Organization Cellular Macromolecule Biosynthetic Process Protein Autoubiquitination Protein Oligomerization Histone Acetylation Vesicle-mediated Transport Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Regulation Of Centriole Replication Histone H4 Acetylation Internal Protein Amino Acid Acetylation Pteridine-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Negative Regulation Of Gene Expression Protein Acetylation DNA Recombination Histone H2A Acetylation Cellular Metabolic Process Neuron Projection Extension Negative Regulation Of Centrosome Duplication Cell Growth Negative Regulation Of Cell Growth Histone Modification	Negative Regulation Of Signal Transduction Regulation Of Gene Expression Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Signal Transduction Negative Regulation Of Signaling Positive Regulation Of Cell Cycle Regulation Of Signaling Positive Regulation Of Histone H4-K20 Methylation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Viral Process Neuromuscular Process Controlling Balance Synapse Assembly Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Histone H3-T6 Phosphorylation Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Regulation Of Synapse Structure Or Activity Regulation Of Nitrogen Compound Metabolic Process Response To Radiation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Collateral Sprouting In Absence Of Injury Gephyrin Clustering Synaptic Vesicle Clustering Regulation Of Receptor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Angiogenesis Response To Tumor Necrosis Factor Neuronal Signal Transduction Regulation Of Response To DNA Damage Stimulus Response To Abiotic Stimulus Neuromuscular Process Positive Regulation Of Cellular Protein Metabolic Process Learning Cellular Response To Indole-3-methanol Collateral Sprouting Axon Midline Choice Point Recognition Non-canonical Wnt Signaling Pathway Via JNK Cascade N-methyl-D-aspartate Receptor Clustering Vocal Learning Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Binding
Tagcloud ?		17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned
Tagcloud (Difference) ?		17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned
Tagcloud (Intersection) ?