FXR2 and RALYL

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXR2	RALYL
Gene Name		fragile X mental retardation, autosomal homolog 2	RALY RNA binding protein-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Polysome Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding	Nucleotide Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		IgM levels ( 23118916) Sex hormone-binding globulin levels ( 22675492)
Protein-Protein Interactions		90 interactors: AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2D CBS CCDC33 CCDC85B CDKL3 CEP44 CEP55 COIL CYFIP1 CYFIP2 DPPA2 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 HMBOX1 HNRNPC KCNRG KCTD4 KIAA1217 KIF1A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDN NECAB2 NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PIM1 POM121 PRAM1 PSME3 PTS RABAC1 RALYL RBBP8 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SRPK2 SSSCA1 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF451 ZSCAN1	17 interactors: AEBP2 AEN BYSL C20orf27 CCDC85B CEP170P1 EWSR1 FXR2 HNRNPC LMO3 LRRK2 MCRS1 PSMF1 RBM41 THAP1 TSNAX ZNF408
Entrez ID		9513	138046
HPRD ID		05629	11236
Ensembl ID		ENSG00000129245	ENSG00000184672
Uniprot IDs		P51116	B3KSX3 B3KT61 G3V129 Q86SE5
PDB IDs		3H8Z
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Negative Regulation Of Centriole Replication Macromolecule Biosynthetic Process Developmental Cell Growth Protein Homooligomerization Tetrahydrobiopterin Biosynthetic Process Pteridine-containing Compound Biosynthetic Process Endoplasmic Reticulum Tubular Network Organization Cellular Macromolecule Biosynthetic Process Protein Autoubiquitination Protein Oligomerization Histone Acetylation Vesicle-mediated Transport Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Regulation Of Centriole Replication Histone H4 Acetylation Internal Protein Amino Acid Acetylation Pteridine-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Negative Regulation Of Gene Expression Protein Acetylation DNA Recombination Histone H2A Acetylation Cellular Metabolic Process Neuron Projection Extension Negative Regulation Of Centrosome Duplication Cell Growth Negative Regulation Of Cell Growth Histone Modification	Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Negative Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Thioredoxin Peroxidase Activity By Peptidyl-threonine Phosphorylation Negative Regulation Of Peroxidase Activity Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Autoubiquitination Negative Regulation Of Late Endosome To Lysosome Transport Regulation Of Protein Autoubiquitination Positive Regulation Of Dopamine Receptor Signaling Pathway Cellular Response To Dopamine Signal Transduction By P53 Class Mediator Regulation Of Protein Targeting To Mitochondrion Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Kidney Size Regulation Of Fat Cell Differentiation Cellular Response To Manganese Ion Positive Regulation Of Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Intracellular Distribution Of Mitochondria Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Neuron Maturation Tangential Migration From The Subventricular Zone To The Olfactory Bulb Regulation Of Nitrogen Compound Metabolic Process Chromatin Modification Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway 3'-UTR-mediated MRNA Stabilization Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Protein Ubiquitination Negative Regulation Of Hydrogen Peroxide-induced Cell Death Locomotory Exploration Behavior Regulation Of Mitochondrial Fission Positive Regulation Of Protein Catabolic Process Histone H4-K5 Acetylation
Tagcloud ?		17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned
Tagcloud (Difference) ?		17p13 adipocytes array cgh disability duplication dysmorphic encodes encompassing facial fingers fissures glut4 hyperpigmentation intellectual mandible nlgn2 nostrils obesity p13 palpebral proposita recognizable referred seizures slc2a4 slender tp53 upturned
Tagcloud (Intersection) ?