RGS16 and GNA13

Number of citations of the paper that reports this interaction (PMID 14634662)
9

Data Source:
HPRD (in vivo, in vitro)

		RGS16	GNA13
Gene Name		regulator of G-protein signaling 16	guanine nucleotide binding protein (G protein), alpha 13
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane	Nucleus Heterotrimeric G-protein Complex Plasma Membrane Focal Adhesion Membrane Brush Border Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Calmodulin Binding	GTPase Activity Signal Transducer Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding Type 1 Angiotensin Receptor Binding D5 Dopamine Receptor Binding Metal Ion Binding
	Biological Process	Visual Perception Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Patterning Of Blood Vessels In Utero Embryonic Development Movement Of Cell Or Subcellular Component Signal Transduction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Rho Protein Signal Transduction Blood Coagulation Regulation Of Cell Shape Cell Differentiation Platelet Activation Regulation Of Cell Migration Activation Of Phospholipase D Activity
Pathways			Thrombin signalling through proteinase activated receptors (PARs) Signaling by GPCR GPCR downstream signaling Thromboxane signalling through TP receptor G alpha (12/13) signalling events Signal amplification Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CREB3L2 CSK EGFR GDE1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAT1 LYN SRC ST14	31 interactors: AIP AKAP3 ARHGEF1 ARHGEF11 ARHGEF12 CDH1 CDH2 CTNNB1 CXCR4 DRD5 EDNRB F2R GNA12 GPR17 MCF2 MTNR1A PPP5C PRKACA PRKCB PRKCD PRKCE PTK2B RDX RGS16 RIC8A S1PR2 S1PR3 S1PR4 TBXA2R TGFBR1 TSHR
Entrez ID		6004	10672
HPRD ID		03945	05100
Ensembl ID		ENSG00000143333	ENSG00000120063
Uniprot IDs		O15492	B7Z7R0 F5H1G8 Q14344
PDB IDs		2BT2 2IK8
Enriched GO Terms of Interacting Partners?		Platelet Activation Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Positive Regulation Of Catalytic Activity Cell Surface Receptor Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Response To Stress Signal Transduction Peptidyl-tyrosine Autophosphorylation G-protein Coupled Receptor Signaling Pathway Signaling Regulation Of Protein Kinase Activity Cell Differentiation Positive Regulation Of Metabolic Process Cell Communication Regulation Of Kinase Activity Regulation Of Intracellular Transport Regulation Of ERK1 And ERK2 Cascade Response To Organonitrogen Compound Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Protein Autophosphorylation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Organ Development Neuron Development Central Nervous System Development Cellular Response To Stimulus Positive Regulation Of Phospholipase Activity T Cell Costimulation Positive Regulation Of Transferase Activity System Development Regulation Of Phospholipase Activity Regulation Of Protein Phosphorylation Neurogenesis Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lipase Activity Regulation Of MAPK Cascade Regulation Of MAP Kinase Activity Regulation Of Protein Transport Tissue Development Neuron Differentiation Regulation Of Establishment Of Protein Localization	Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Signal Transduction Positive Regulation Of Catalytic Activity Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis G-protein Coupled Receptor Signaling Pathway Signaling Regulation Of Signaling Cell Communication Regulation Of Catalytic Activity Regulation Of Signal Transduction Cellular Response To Stimulus Cytosolic Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Activation Cellular Chemical Homeostasis Ion Homeostasis Apoptotic Process Programmed Cell Death Response To Stimulus Positive Regulation Of Hydrolase Activity Cellular Response To Organic Substance Cell Death Death Chemical Homeostasis Cellular Homeostasis Regulation Of Cellular Process G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Intracellular Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Regulation Of MAPK Cascade Platelet Activation Homeostatic Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Signaling Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Neurotrophin Signaling Pathway Positive Regulation Of Cellular Metabolic Process Termination Of Signal Transduction
Tagcloud ?		aspc bxpc candidates coexpressing cooperate cross discovery downregulated exogenously inactivated inhibit inhibiting invasion metastases migration oncogenic p53 panc pancreatic prb profiling rb1 reoccurrence suppressors talk toward tumorigenesis viability wi38	18q 19p13 1q aberrations arising burkitt collaborating cooperate copy deep enhancer gains id3 immunoglobulin lymphoma microrna myc next profiling recurrent scope sequencing signatures smarca4 subgroups summary transcriptome widened yielded
Tagcloud (Difference) ?		aspc bxpc candidates coexpressing cross discovery downregulated exogenously inactivated inhibit inhibiting invasion metastases migration oncogenic p53 panc pancreatic prb rb1 reoccurrence suppressors talk toward tumorigenesis viability wi38	18q 19p13 1q aberrations arising burkitt collaborating copy deep enhancer gains id3 immunoglobulin lymphoma microrna myc next recurrent scope sequencing signatures smarca4 subgroups summary transcriptome widened yielded
Tagcloud (Intersection) ?		cooperate profiling