RGS16 and GNAI3

Number of citations of the paper that reports this interaction (PubMedID 9079700)
0

Data Source:
HPRD (in vitro)

		RGS16	GNAI3
Description		regulator of G protein signaling 16	G protein subunit alpha i3
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Golgi Membrane Nucleoplasm Nucleolus Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Centrosome Cytosol Heterotrimeric G-protein Complex Cytoskeleton Plasma Membrane Membrane Midbody Centriolar Satellite Ciliary Basal Body Extracellular Exosome
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding Calmodulin Binding	Nucleotide Binding G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding Guanyl Nucleotide Binding GDP Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Macroautophagy GTP Metabolic Process Cell Division
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events	Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway ADP signalling through P2Y purinoceptor 12 G alpha (s) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events Extra-nuclear estrogen signaling GPER1 signaling ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Chronotype ( 26955885 27494321 30696823) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600 26955885 27494321) Sleep traits (multi-trait analysis) ( 27992416)	Childhood body mass index ( 33045005) Major depressive disorder ( 20125088)
Interacting Genes		14 interacting genes: CREB3L2 CSK EGFR GDE1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAT1 LYN SRC ST14	45 interacting genes: AGTR2 ATP12A CCDC88A CCDC88C CCR5 CD48 CD59 CNR1 CXCR2 DRD2 DVL1 GNB2 GNB4 GPSM1 GPSM2 GPSM3 HTR1A LPAR1 MTNR1A MTNR1B NGB NUCB1 NUCB2 PCP2 PHF24 PRKAR2B PTPRU RANGAP1 RGS10 RGS12 RGS14 RGS16 RGS17 RGS18 RGS19 RGS2 RGS20 RGS3 RGS5 RGS7 RIC8A S1PR1 SNCA SOX30 TSHR
Entrez ID		6004	2773
HPRD ID		03945	00765
Ensembl ID		ENSG00000143333	ENSG00000065135
Uniprot IDs		O15492	P08754
PDB IDs		2BT2 2IK8	2IHB 2ODE 2V4Z 4G5O 4G5R 4G5S 7E9H 7KH0 7RA3 7RGP 7T10 7T11 7X6I 8GVX 8JD6 8K9L 8OY1 8SZH 8SZI 8WGB 9AVL
Enriched GO Terms of Interacting Partners?		Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex G Protein-coupled Receptor Binding Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway GTPase Activity Nucleotide Binding GTP Binding G Protein Activity Plasma Membrane Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Serotonin Receptor Signaling Pathway G Protein-coupled Serotonin Receptor Binding Regulation Of ERK1 And ERK2 Cascade Membrane Protein Tyrosine Kinase Activity Adenylate Cyclase Regulator Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Protein Localization To Cell Periphery T Cell Costimulation Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Catalytic Activity Signaling Receptor Activator Activity Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity GDP Binding Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Protein Localization To Cell Periphery Signal Transduction Regulation Of Cell Communication Regulation Of Protein Localization Regulation Of Signaling Phototransduction, Visible Light Regulation Of Catalytic Activity Extracellular Exosome Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Tyrosine Kinase Activator Activity Response To Peptide Hormone Response To Hormone Ciliary Basal Body Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Protein Transport Regulation Of MAPK Cascade G Protein-coupled Acetylcholine Receptor Signaling Pathway Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis ERBB2 Signaling Pathway	G Protein-coupled Receptor Signaling Pathway G-protein Alpha-subunit Binding Signal Transduction Regulation Of G Protein-coupled Receptor Signaling Pathway Plasma Membrane GTPase Activity GTPase Activator Activity Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling GTPase Regulator Activity GDP-dissociation Inhibitor Activity G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Signal Transduction Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Membrane Synapse Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Guanyl-nucleotide Exchange Factor Activity Dendrite Regulation Of GTPase Activity Cytoplasm Melatonin Receptor Activity Dendritic Spine Response To Amphetamine Positive Regulation Of GTPase Activity Signaling Receptor Complex Adaptor Activity Glutamatergic Synapse Dopamine Uptake Involved In Synaptic Transmission Cell-cell Signaling Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Dopamine Uptake Involved In Synaptic Transmission Signaling Response To Amine Positive Regulation Of Hydrolase Activity Cell Communication Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Intracellular Signaling Cassette Presynapse Catecholamine Uptake Dopamine Uptake Visual Learning Presynaptic Membrane Regulation Of Blood Circulation Visual Behavior
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?