RALB and REPS1

Number of citations of the paper that reports this interaction (PMID 9422736)
27

Data Source:
HPRD (in vitro)

		RALB	REPS1
Gene Name		v-ral simian leukemia viral oncogene homolog B	RALBP1 associated Eps domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Autophagic Vacuole Plasma Membrane Midbody Extracellular Vesicular Exosome	Plasma Membrane Coated Pit
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding	Calcium Ion Binding Protein Binding SH3 Domain Binding
	Biological Process	Cytokinesis Regulation Of Exocyst Assembly Positive Regulation Of Protein Phosphorylation Apoptotic Process Signal Transduction Ras Protein Signal Transduction Cellular Response To Starvation Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Neurotrophin TRK Receptor Signaling Pathway Regulation Of Exocyst Localization Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Autophagic Vacuole Assembly	Receptor-mediated Endocytosis
Pathways		Signalling to ERKs Signalling by NGF Signalling to RAS p38MAPK events NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CALM1 PLCD1 RALBP1 REPS1 REPS2 RGL4	13 interactors: ATF4 CRK GRB2 HSF1 ITSN2 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2L WWC2
Entrez ID		5899	85021
HPRD ID		01550	09687
Ensembl ID		ENSG00000144118	ENSG00000135597
Uniprot IDs		B4E040 P11234 Q6ZS74	J3KP76 Q96D71
PDB IDs		2KE5 2KWI
Enriched GO Terms of Interacting Partners?		Inositol Phosphate Metabolic Process Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Hydrolase Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Signal Transduction Detection Of Calcium Ion Alcohol Metabolic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Signaling Cell Communication Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Cdc42 GTPase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Cdc42 GTPase Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Labyrinthine Layer Blood Vessel Development Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Autophosphorylation Cellular Response To Stimulus Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine	Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Rho GTPase Activity Response To Organic Substance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Regulation Of Rho Protein Signal Transduction Vesicle-mediated Transport Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Regulation Of Ras GTPase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Transferase Activity Ras Protein Signal Transduction Cellular Response To Growth Factor Stimulus Response To External Stimulus Response To Growth Factor Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Cellular Response To Stimulus Regulation Of Ras Protein Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Small GTPase Mediated Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Exocyst Assembly Signaling Regulation Of GTPase Activity Cell Communication Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Phosphorylation Regulation Of Exocyst Localization Positive Regulation Of Autophagic Vacuole Assembly Positive Regulation Of Vacuole Organization Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Ras GTPase Activity Cytokinesis Positive Regulation Of Hydrolase Activity Embryonic Placenta Development Positive Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of Kinase Activity Intracellular Signal Transduction
Tagcloud ?		adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed
Tagcloud (Difference) ?		adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed
Tagcloud (Intersection) ?