RALB and REPS1

Number of citations of the paper that reports this interaction (PubMedID 9422736)
0

Data Source:
HPRD (in vitro)

		RALB	REPS1
Description		RAS like proto-oncogene B	RALBP1 associated Eps domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Midbody Extracellular Exosome	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding	Calcium Ion Binding Protein Binding SH3 Domain Binding Protein-macromolecule Adaptor Activity Metal Ion Binding
	Biological Process	Regulation Of Exocyst Assembly Apoptotic Process Signal Transduction Ras Protein Signal Transduction Receptor Internalization Positive Regulation Of Innate Immune Response Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Division Regulation Of Exocyst Localization Positive Regulation Of Autophagosome Assembly	Endocytosis Endosomal Transport
Pathways		p38MAPK events	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Breast size ( 27182965) Intraocular pressure ( 29617998) Mean platelet volume ( 27863252 32888494) Metabolite levels ( 23823483) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834) Type 2 diabetes ( 32499647)
Interacting Genes		7 interacting genes: CALM1 INCA1 PLCD1 RALBP1 REPS1 REPS2 RGL4	19 interacting genes: AKT1 ANKRD1 ATF4 CRK FLNC GRB2 HSF1 ITSN1 ITSN2 MZT1 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2 TRAPPC2L WWC2
Entrez ID		5899	85021
HPRD ID		01550	09687
Ensembl ID		ENSG00000144118	ENSG00000135597
Uniprot IDs		P11234	B2R7D3 Q96D71
PDB IDs		2KE5 2KWI 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?		Endocytosis Intracellular Signaling Cassette Import Into Cell Calcium Ion Binding Signal Transduction Intracellular Signal Transduction Plasma Membrane C-X-C Motif Chemokine 12 Receptor Activity Doxorubicin Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Vesicle-mediated Transport Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Calcium-mediated Signaling Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Autophagosome Membrane Docking Spindle Pole Phosphatidylinositol Phospholipase C Activity Anion Binding Phospholipase C/protein Kinase C Signal Transduction CXCL12-activated CXCR4 Signaling Pathway Myosin Light Chain Binding Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway C-X-C Chemokine Receptor CXCR4 Signaling Pathway Negative Regulation Of Voltage-gated Calcium Channel Activity Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway C-X-C Chemokine Receptor Activity ABC-type Glutathione S-conjugate Transporter Activity Protein-macromolecule Adaptor Activity Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity	Vesicle-mediated Transport Endocytosis Receptor-mediated Endocytosis Intracellular Signaling Cassette Import Into Cell Intracellular Signal Transduction Clathrin-dependent Synaptic Vesicle Endocytosis Cytosol Protein-macromolecule Adaptor Activity Small GTPase-mediated Signal Transduction Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Regulation Of Signal Transduction Positive Regulation Of Organelle Organization Signal Transduction Organelle Organization Cellular Response To Decreased Oxygen Levels Response To Decreased Oxygen Levels Regulation Of Organelle Organization Cellular Response To Oxygen Levels Response To Oxygen Levels Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling PERK-mediated Unfolded Protein Response Receptor Internalization Establishment Of Protein Localization To Mitochondrion General Transcription Initiation Factor Binding TRAPPII Protein Complex TRAPPIII Protein Complex ERBB Signaling Pathway Ras Protein Signal Transduction Regulation Of Innate Immune Response Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Kinase Binding Cellular Localization Positive Regulation Of Protein Localization To Membrane Regulation Of Intracellular Signal Transduction TRAPP Complex Cytoplasm Positive Regulation Of Growth Positive Regulation Of Organelle Assembly Kinase Binding Positive Regulation Of Cellular Component Biogenesis Intracellular Vesicle Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Organization Response To Hypoxia
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