RALB and RALBP1

Number of citations of the paper that reports this interaction (PMID 7673236)
86

Data Source:
HPRD (in vitro, two hybrid)

		RALB	RALBP1
Gene Name		v-ral simian leukemia viral oncogene homolog B	ralA binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Exocyst Autophagic Vacuole Plasma Membrane Midbody Extracellular Vesicular Exosome	Cytosol Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding	GTPase Activator Activity Protein Binding ATPase Activity Ral GTPase Binding Rac GTPase Activator Activity ATPase Activity, Coupled To Movement Of Substances Rac GTPase Binding
	Biological Process	Cytokinesis Regulation Of Exocyst Assembly Positive Regulation Of Protein Phosphorylation Apoptotic Process Signal Transduction Ras Protein Signal Transduction Cellular Response To Starvation Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Neurotrophin TRK Receptor Signaling Pathway Regulation Of Exocyst Localization Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Autophagic Vacuole Assembly	Transport Chemotaxis Signal Transduction Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Rac GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Cdc42 GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Signalling to ERKs Signalling by NGF Signalling to RAS p38MAPK events NGF signalling via TRKA from the plasma membrane	Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CALM1 PLCD1 RALBP1 REPS1 REPS2 RGL4	27 interactors: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GPS2 GSE1 HOOK2 HSF1 IKBKG PPL PRKCA RAC1 RALA RALB REPS1 REPS2 SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 ZBTB38 ZNF707
Entrez ID		5899	10928
HPRD ID		01550	09013
Ensembl ID		ENSG00000144118	ENSG00000017797
Uniprot IDs		B4E040 P11234 Q6ZS74	Q15311
PDB IDs		2KE5 2KWI	2KWH 2KWI
Enriched GO Terms of Interacting Partners?		Inositol Phosphate Metabolic Process Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Hydrolase Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Signal Transduction Detection Of Calcium Ion Alcohol Metabolic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Signaling Cell Communication Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Cdc42 GTPase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Cdc42 GTPase Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Labyrinthine Layer Blood Vessel Development Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Autophosphorylation Cellular Response To Stimulus Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine	Toll-like Receptor Signaling Pathway Positive Regulation Of Macrophage Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin Signaling Pathway TRAIL-activated Apoptotic Signaling Pathway Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Innate Immune Response Programmed Cell Death Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Response To External Stimulus Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Localization Viral Process Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Apoptotic Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Growth Factor Cellular Response To Stimulus Regulation Of Immune System Process Regulation Of Phosphorylation Positive Regulation Of Immune Response Signal Transduction Defense Response Cell Cycle Positive Regulation Of Metabolic Process Negative Regulation Of Intracellular Signal Transduction Protein Complex Assembly Response To Stress Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Myeloid Cell Differentiation
Tagcloud ?		adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed	abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways
Tagcloud (Difference) ?		adoptive antitumor capability chimeric combining engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto recognition recognize regressions remarkable retrovirally termed	abrogate complemented counteracts cytoplasmic downstream equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 ras ser thr transforming ways
Tagcloud (Intersection) ?		effectors rala