RALB and REPS2

Number of citations of the paper that reports this interaction (PMID 9422736)
27

Data Source:
HPRD (in vitro)

		RALB	REPS2
Gene Name		v-ral simian leukemia viral oncogene homolog B	RALBP1 associated Eps domain containing 2
Image
Gene Ontology Annotations	Cellular Component	Exocyst Autophagic Vacuole Plasma Membrane Midbody Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding	Calcium Ion Binding Protein Binding
	Biological Process	Cytokinesis Regulation Of Exocyst Assembly Positive Regulation Of Protein Phosphorylation Apoptotic Process Signal Transduction Ras Protein Signal Transduction Cellular Response To Starvation Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Neurotrophin TRK Receptor Signaling Pathway Regulation Of Exocyst Localization Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Autophagic Vacuole Assembly	Protein Complex Assembly Epidermal Growth Factor Receptor Signaling Pathway
Pathways		Signalling to ERKs Signalling by NGF Signalling to RAS p38MAPK events NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CALM1 PLCD1 RALBP1 REPS1 REPS2 RGL4	13 interactors: AR ASAP1 ASAP2 CDK1 CDK5RAP2 EPN1 EPS15 GRB2 PXN RALB RALBP1 RELA REPS1
Entrez ID		5899	9185
HPRD ID		01550	02262
Ensembl ID		ENSG00000144118	ENSG00000169891
Uniprot IDs		B4E040 P11234 Q6ZS74	B4DQQ8 Q8NFH8
PDB IDs		2KE5 2KWI	1IQ3
Enriched GO Terms of Interacting Partners?		Inositol Phosphate Metabolic Process Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Hydrolase Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Signal Transduction Detection Of Calcium Ion Alcohol Metabolic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Signaling Cell Communication Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Cdc42 GTPase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Cdc42 GTPase Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Labyrinthine Layer Blood Vessel Development Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Autophosphorylation Cellular Response To Stimulus Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Regulation Of Schwann Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Hormone Stimulus Cellular Response To Growth Factor Stimulus Regulation Of ERBB Signaling Pathway Response To Growth Factor Regulation Of Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Reactive Oxygen Species Cellular Response To Peptide Positive Regulation Of Catalytic Activity Response To Peptide Hormone Response To Hormone Cellular Response To Organonitrogen Compound Response To Peptide Response To Reactive Oxygen Species Protein Complex Assembly Cellular Response To Oxidative Stress Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Ras Protein Signal Transduction Fc-epsilon Receptor Signaling Pathway Cellular Response To Organic Substance Small GTPase Mediated Signal Transduction Negative Regulation Of Signaling Endocytosis Signal Transduction Fc Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Toll-like Receptor 10 Signaling Pathway Regulation Of Phosphorylation Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Cellular Response To Hydrogen Peroxide Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway
Tagcloud ?		adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed	amphiphysin arrays bioinformatics bridging cytoskeleton differently ectopic endocytosis leaving linking machinery mammals motifs mutagenic partner phage pob1 predictions proline ralbp1 recruiting rich scaffold sh3 spaced traffic transferrin unaffected vesicular
Tagcloud (Difference) ?		adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed	amphiphysin arrays bioinformatics bridging cytoskeleton differently ectopic endocytosis leaving linking machinery mammals motifs mutagenic partner phage pob1 predictions proline ralbp1 recruiting rich scaffold sh3 spaced traffic transferrin unaffected vesicular
Tagcloud (Intersection) ?