RALB

Description		RAS like proto-oncogene B
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GO Annotations	Cellular Component	Plasma Membrane Membrane Midbody Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding
	Biological Process	Regulation Of Exocyst Assembly Apoptotic Process Signal Transduction Ras Protein Signal Transduction Receptor Internalization Positive Regulation Of Innate Immune Response Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Division Regulation Of Exocyst Localization Positive Regulation Of Autophagosome Assembly
Pathways		p38MAPK events
Drugs
Diseases
GWAS		Breast size ( 27182965) Intraocular pressure ( 29617998) Mean platelet volume ( 27863252 32888494) Metabolite levels ( 23823483) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Novel Interacting Genes		1 novel interacting genes: CXCR4
Interacting Genes		7 interacting genes: CALM1 INCA1 PLCD1 RALBP1 REPS1 REPS2 RGL4
Entrez ID		5899
HPRD ID		01550
Ensembl ID		ENSG00000144118
Uniprot IDs		P11234
PDB IDs		2KE5 2KWI 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?		Endocytosis Intracellular Signaling Cassette Import Into Cell Calcium Ion Binding Signal Transduction Intracellular Signal Transduction Plasma Membrane C-X-C Motif Chemokine 12 Receptor Activity Doxorubicin Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Vesicle-mediated Transport Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Calcium-mediated Signaling Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Autophagosome Membrane Docking Spindle Pole Phosphatidylinositol Phospholipase C Activity Anion Binding Phospholipase C/protein Kinase C Signal Transduction CXCL12-activated CXCR4 Signaling Pathway Myosin Light Chain Binding Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway C-X-C Chemokine Receptor CXCR4 Signaling Pathway Negative Regulation Of Voltage-gated Calcium Channel Activity Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway C-X-C Chemokine Receptor Activity ABC-type Glutathione S-conjugate Transporter Activity Protein-macromolecule Adaptor Activity Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
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