RIN1

Gene Name		Ras and Rab interactor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Dendrite Neuronal Cell Body
	Molecular Function	GTPase Activator Activity Protein Binding Ras GTPase Binding
	Biological Process	Endocytosis Signal Transduction Memory Associative Learning Negative Regulation Of Synaptic Plasticity Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-protein Interactions		15 interactors: ABL1 ABL2 CALCOCO2 ERBB2 ERBB3 HRAS LZTS2 MLLT4 RAB5A RAB5B RALGDS RRAS2 YWHAB YWHAE YWHAZ
Entrez ID		9610
HPRD ID		05813
Ensembl ID		ENSG00000174791
Uniprot IDs		Q13671
PDB IDs
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Intracellular Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Regulation Of Signaling Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Signaling Cell Communication Apoptotic Signaling Pathway Regulation Of Signal Transduction Intrinsic Apoptotic Signaling Pathway Response To Stimulus Cellular Response To Stimulus Innate Immune Response Positive Regulation Of Signal Transduction Immune Response Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Defense Response Regulation Of Cellular Component Organization Fc Receptor Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Response To Growth Factor Stimulus Wound Healing Response To Growth Factor Small GTPase Mediated Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Catalytic Activity Immune System Process Regulation Of Cell Death Regulation Of Cellular Localization Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Interferon-gamma Secretion Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Response To Wounding Regulation Of Catalytic Activity Axon Guidance Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Transport Regulation Of Intracellular Signal Transduction Glial Cell Differentiation Regulation Of Endocytosis Response To Organic Substance Negative Regulation Of Protein Dephosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Protein Localization
Tagcloud ?		abcc12 braf dabrafenib deregulated deserve detoxification discover exploratory highlighted invasiveness klf17 melanoma mtefd1 nqo1 peaks rbm10 responder responders seldi silico slain1 strongest surrogates tox3 tspo2 v600 vemurafenib z zbtb44