RIN1 and CALCOCO2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RIN1	CALCOCO2
Gene Name		Ras and Rab interactor 1	calcium binding and coiled-coil domain 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Dendrite Neuronal Cell Body	Nucleus Cytoplasm Golgi Apparatus Cytoskeleton Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Ras GTPase Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Endocytosis Signal Transduction Memory Associative Learning Negative Regulation Of Synaptic Plasticity Positive Regulation Of GTPase Activity	Viral Process Response To Interferon-gamma
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		15 interactors: ABL1 ABL2 CALCOCO2 ERBB2 ERBB3 HRAS LZTS2 MLLT4 RAB5A RAB5B RALGDS RRAS2 YWHAB YWHAE YWHAZ	143 interactors: ABLIM1 ADSL AES AKAP17A AMMECR1 AP5B1 APEX2 ARHGEF39 ARHGEF5 ARNT2 BAHD1 BCL6B BEX2 C20orf195 CBX8 CCDC185 CCDC33 CCNH CEP57L1 CHCHD3 CPNE7 CWF19L2 DAXX DAZAP2 DBNDD2 DCTN4 DCX DDIT4L DDX6 DOCK2 DUSP12 DUSP26 EEF1E1 ENKD1 EXOSC5 FAM107A FAM161A FAM168A FAM189A2 FAM90A1 FARS2 FASTK FBF1 FBXL18 FKBPL FXR2 GABARAPL1 GABARAPL2 GATAD2B GEMIN4 GIT2 GLYCTK HDAC7 HOXB9 IKBKG KANSL1 KAT7 KLHL42 LENG1 LGALS8 LIMS2 LITAF LMF2 LMO2 LMO4 LNX1 LONRF1 LSM4 MAGOHB MAVS MCM10 METTL17 MID2 MOS MTPAP MVP MXI1 MYO6 NAA10 NDN NFU1 ORC5 PAPD4 PCGF1 PEF1 PEG10 PFDN5 PHF1 PIAS4 POLI PPP1R18 PRKAB2 PRPF31 PSMA1 PSME4 PTBP1 PTBP2 RABL6 RB1CC1 RBM15 RHPN1 RIN1 RNF11 RPA2 RPL9 RPS27A RTN4IP1 RTP5 SDCBP SHC1 SLC15A3 SMARCD1 SMCP SNRPB SPATA24 SRI STK16 TAX1BP1 TBC1D22B TBK1 TBRG4 TCEB3B TCL1A TEKT3 TP53RK TRAF2 TRAF4 TRAF6 UBAC2 UBB UBC VARS VPS72 ZC2HC1C ZNF101 ZNF205 ZNF337 ZNF408 ZNF426 ZNF451 ZNF564 ZNF581 ZNF638
Entrez ID		9610	10241
HPRD ID		05813	06846
Ensembl ID		ENSG00000174791	ENSG00000136436
Uniprot IDs		Q13671	Q13137
PDB IDs			3VVV 3VVW 4GXL 4HAN
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Intracellular Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Regulation Of Signaling Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Signaling Cell Communication Apoptotic Signaling Pathway Regulation Of Signal Transduction Intrinsic Apoptotic Signaling Pathway Response To Stimulus Cellular Response To Stimulus Innate Immune Response Positive Regulation Of Signal Transduction Immune Response Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Defense Response Regulation Of Cellular Component Organization Fc Receptor Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Response To Growth Factor Stimulus Wound Healing Response To Growth Factor Small GTPase Mediated Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Catalytic Activity Immune System Process Regulation Of Cell Death Regulation Of Cellular Localization Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Interferon-gamma Secretion Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Response To Wounding Regulation Of Catalytic Activity Axon Guidance Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Transport Regulation Of Intracellular Signal Transduction Glial Cell Differentiation Regulation Of Endocytosis Response To Organic Substance Negative Regulation Of Protein Dephosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Protein Localization	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Type I Interferon Production MRNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Toll-like Receptor 4 Signaling Pathway Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter JNK Cascade Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Protein Modification By Small Protein Conjugation Activation Of MAPK Activity Activation Of Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Signaling Positive Regulation Of Protein Modification Process Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Type I Interferon Production Activation Of NF-kappaB-inducing Kinase Activity Protein Ubiquitination Toll-like Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity G1/S Transition Of Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint
Tagcloud ?		abcc12 braf dabrafenib deregulated deserve detoxification discover exploratory highlighted invasiveness klf17 melanoma mtefd1 nqo1 peaks rbm10 responder responders seldi silico slain1 strongest surrogates tox3 tspo2 v600 vemurafenib z zbtb44	ad astrocytes atg atgs autophagic autophagy avs beneficial brains clear clearance enhancement expected facilitating flux hippocampal impairment lc3 localized microglia mouse ndp52 p62 phosphorylated plaques reflecting sqstm1 tau vesicles
Tagcloud (Difference) ?		abcc12 braf dabrafenib deregulated deserve detoxification discover exploratory highlighted invasiveness klf17 melanoma mtefd1 nqo1 peaks rbm10 responder responders seldi silico slain1 strongest surrogates tox3 tspo2 v600 vemurafenib z zbtb44	ad astrocytes atg atgs autophagic autophagy avs beneficial brains clear clearance enhancement expected facilitating flux hippocampal impairment lc3 localized microglia mouse ndp52 p62 phosphorylated plaques reflecting sqstm1 tau vesicles
Tagcloud (Intersection) ?