RIN1 and KRTAP13-1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		RIN1	KRTAP13-1
Description		Ras and Rab interactor 1	keratin associated protein 13-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Endocytic Vesicle	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	Structural Molecule Activity
	Biological Process	Endocytosis Signal Transduction Vesicle-mediated Transport Intracellular Signal Transduction
Pathways		RAB GEFs exchange GTP for GDP on RABs	Keratinization
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Treatment resistant depression ( 30468137)
Interacting Genes		49 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP ITSN1 KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1	43 interacting genes: ARMC7 ATXN1L BAG4 BANF2 BCL6 CFAP206 CHRD COL8A1 CRACR2A FAM221B GLRX3 KLHL38 KRT34 KRTAP10-3 KRTAP10-5 KRTAP12-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LONRF1 MAPKBP1 MEIS2 NEK6 NMUR2 NOXA1 OTX1 PITX1 POU4F2 PROP1 PRR13 PSPC1 RANBP3 RBPMS RIN1 SCAMP1 STK16 TBC1D10C TBX6 TEKT4 TNS2 UBQLN2 VENTX YTHDF1
Entrez ID		9610	140258
HPRD ID		05813	10570
Ensembl ID		ENSG00000174791	ENSG00000198390
Uniprot IDs		A0A0S2Z4T5 A0A0S2Z4U0 Q13671	Q8IUC0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytosol Cytoplasm Perinuclear Region Of Cytoplasm Phosphoserine Residue Binding Epidermal Growth Factor Receptor Signaling Pathway Regulation Of MAPK Cascade ERBB Signaling Pathway GDP Binding Intracellular Signaling Cassette MAPK Cascade Identical Protein Binding Regulation Of Intracellular Signal Transduction Protein Sequestering Activity ERBB3:ERBB2 Complex Regulation Of Autophagy Melanosome Positive Regulation Of Intracellular Signal Transduction Cellular Localization Vesicle-mediated Transport Schwann Cell Development Protein Tyrosine Kinase Activity Glial Cell Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ERBB2 Signaling Pathway Positive Regulation Of MAPK Cascade Establishment Of Protein Localization Positive Regulation Of Establishment Of T Cell Polarity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Binding Establishment Of Localization In Cell Regulation Of Cell Communication Signal Transduction Regulation Of Signaling ErbB-3 Class Receptor Binding Regulation Of Cellular Component Organization Intracellular Transport Regulation Of Actin Filament-based Process Protein Binding Regulation Of Establishment Of T Cell Polarity Regulation Of Signal Transduction Protein Modification Process Regulation Of Fibroblast Proliferation Regulation Of ERK1 And ERK2 Cascade Protein Phosphatase Binding Myelination Axon Ensheathment Regulation Of Protein Localization Negative Regulation Of Signaling Negative Regulation Of Cell Communication ERBB2-EGFR Signaling Pathway	Keratin Filament Intermediate Filament
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