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RIN1 and RRAS2
Number of citations of the paper that reports this interaction (PMID
19060904
)
157
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid, in vivo)
RIN1
RRAS2
Gene Name
Ras and Rab interactor 1
related RAS viral (r-ras) oncogene homolog 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Plasma Membrane
Dendrite
Neuronal Cell Body
Endoplasmic Reticulum
Plasma Membrane
Focal Adhesion
Membrane
Extracellular Vesicular Exosome
Molecular Function
GTPase Activator Activity
Protein Binding
Ras GTPase Binding
GTPase Activity
Protein Binding
GTP Binding
Biological Process
Endocytosis
Signal Transduction
Memory
Associative Learning
Negative Regulation Of Synaptic Plasticity
Positive Regulation Of GTPase Activity
Osteoblast Differentiation
Ras Protein Signal Transduction
Positive Regulation Of Cell Migration
Regulation Of Neuron Death
Pathways
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Alzheimer's disease (cognitive decline) (
23535033
)
Protein-Protein Interactions
15 interactors:
ABL1
ABL2
CALCOCO2
ERBB2
ERBB3
HRAS
LZTS2
MLLT4
RAB5A
RAB5B
RALGDS
RRAS2
YWHAB
YWHAE
YWHAZ
29 interactors:
ACVR1
AHSG
ARAF
ARHGEF2
BMPR1B
CREB3
FNTB
LGALS4
MLLT4
PAWR
PGGT1B
PIK3R1
PTPN1
RABAC1
RAF1
RALGDS
RAPGEF1
RAPGEF3
RAPGEF4
RASGRF1
RASIP1
RASSF5
RIN1
SMAD3
SMAD4
SMURF2
TRAF2
TRAF3
XRCC6
Entrez ID
9610
22800
HPRD ID
05813
02518
Ensembl ID
ENSG00000174791
ENSG00000133818
Uniprot IDs
Q13671
B7Z5Z2
P62070
PDB IDs
2ERY
Enriched GO Terms of Interacting Partners
?
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Intracellular Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Ras Protein Signal Transduction
Neurotrophin Signaling Pathway
Regulation Of Signaling
Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Signaling
Cell Communication
Apoptotic Signaling Pathway
Regulation Of Signal Transduction
Intrinsic Apoptotic Signaling Pathway
Response To Stimulus
Cellular Response To Stimulus
Innate Immune Response
Positive Regulation Of Signal Transduction
Immune Response
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Defense Response
Regulation Of Cellular Component Organization
Fc Receptor Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cellular Response To Growth Factor Stimulus
Wound Healing
Response To Growth Factor
Small GTPase Mediated Signal Transduction
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Catalytic Activity
Immune System Process
Regulation Of Cell Death
Regulation Of Cellular Localization
Regulation Of Actin Cytoskeleton Reorganization
Positive Regulation Of Interferon-gamma Secretion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Response To Wounding
Regulation Of Catalytic Activity
Axon Guidance
Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Transport
Regulation Of Intracellular Signal Transduction
Glial Cell Differentiation
Regulation Of Endocytosis
Response To Organic Substance
Negative Regulation Of Protein Dephosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of Protein Localization
Regulation Of Signaling
Regulation Of Signal Transduction
Regulation Of Metabolic Process
Signal Transduction
Response To Stimulus
Signaling
Cell Communication
Positive Regulation Of Metabolic Process
Cellular Response To Stimulus
Intracellular Signal Transduction
Regulation Of Phosphorylation
Regulation Of Catalytic Activity
Response To Organic Substance
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Response To Organic Substance
Positive Regulation Of Hydrolase Activity
Cellular Response To Growth Factor Stimulus
Regulation Of Protein Phosphorylation
Response To Growth Factor
Regulation Of Intracellular Signal Transduction
Endothelial Cell Differentiation
Positive Regulation Of Catalytic Activity
Regulation Of Cell Death
Endothelium Development
Regulation Of Cellular Protein Metabolic Process
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Cellular Process
Regulation Of GTPase Activity
Response To Stress
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Metabolic Process
Regulation Of Apoptotic Process
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Proliferation
Negative Regulation Of Signaling
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Cell Proliferation
Positive Regulation Of Signal Transduction
Negative Regulation Of Cell Death
Positive Regulation Of Rap GTPase Activity
Positive Regulation Of GTPase Activity
Regulation Of Bone Mineralization
Defense Response
BMP Signaling Pathway
Regulation Of Cytokine Production
Regulation Of Ras GTPase Activity
Regulation Of Protein Localization
Tagcloud
?
abcc12
braf
dabrafenib
deregulated
deserve
detoxification
discover
exploratory
highlighted
invasiveness
klf17
melanoma
mtefd1
nqo1
peaks
rbm10
responder
responders
seldi
silico
slain1
strongest
surrogates
tox3
tspo2
v600
vemurafenib
z
zbtb44
Tagcloud (Difference)
?
abcc12
braf
dabrafenib
deregulated
deserve
detoxification
discover
exploratory
highlighted
invasiveness
klf17
melanoma
mtefd1
nqo1
peaks
rbm10
responder
responders
seldi
silico
slain1
strongest
surrogates
tox3
tspo2
v600
vemurafenib
z
zbtb44
Tagcloud (Intersection)
?