STX4 and STXBP6

Number of citations of the paper that reports this interaction (PubMedID 12145319)
0

Data Source:
HPRD (in vitro, in vivo)

		STX4	STXBP6
Description		syntaxin 4	syntaxin binding protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Storage Vacuole Extracellular Space Cytoplasm Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Cell Surface Endomembrane System Membrane Basolateral Plasma Membrane Lamellipodium Phagocytic Vesicle Membrane SNARE Complex Stereocilium Neuron Projection Membrane Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Cell Projection Neuron Projection Dendritic Spine Lateral Loop Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse	Cytoplasm Adherens Junction Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity	Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Positive Regulation Of Immunoglobulin Production Neurotransmitter Transport Intracellular Protein Transport Exocytosis Vesicle Fusion Sensory Perception Of Sound Positive Regulation Of Cell Population Proliferation Vesicle-mediated Transport Regulation Of Exocytosis Positive Regulation Of Cell Migration Protein Localization To Cell Surface Cellular Response To Oxidative Stress SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Membrane Organization Cellular Response To Type II Interferon Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Cornified Envelope Assembly Positive Regulation Of Protein Localization To Cell Surface	SNARE Complex Assembly Regulation Of SNARE Complex Assembly Negative Regulation Of Exocytosis Cell-cell Adhesion
Pathways		Disinhibition of SNARE formation ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Other interleukin signaling
Drugs
Diseases
GWAS		Response to metformin (IC50) ( 28173075) Triglyceride levels ( 32203549)	Adult body size ( 32376654) Body mass index ( 28892062 28448500 25673413 26961502) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Cataracts ( 34127677) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophil count ( 27863252 32888494) Finger osteoarthritis severity (hand Klsum) ( 33055079) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 28552196 25673412) Hippocampal volume ( 21116278) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494 27863252) Microalbuminuria in type 1 diabetes ( 31537649) Monocyte count ( 32888494 27863252 29403010) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neuritic plaque ( 31497858) Neutrophil count ( 29403010 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Overweight status ( 25133637) Peanut allergy ( 29030101) Platelet count ( 32888494) Plateletcrit ( 32888494) Protein level change in low calorie diet obesity intervention ( 29234017) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Subcutaneous adipose tissue ( 22589738) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Waist circumference ( 25673412) White blood cell count ( 29403010 27863252 32888494) White blood cell types ( 21738478) Zinc levels ( 26025379)
Interacting Genes		65 interacting genes: ABI2 ACTB ANKRD46 BET1 CYBRD1 DLG1 DNAJC5 FAXDC2 GIMAP5 GOSR2 GPR152 ITSN2 LLGL1 LMNA NAPA NAPB NSF PLP1 PSMA3 RAB11A RAB4A RAB5A RNF4 SCRIB SEC22A SEC22B SEPTIN5 SERP1 SGPL1 SH3GLB2 SNAP23 SNAP25 SNAP47 STX10 STX11 STX16 STX1A STX1B STX2 STX3 STX5 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TCEANC TMEM203 TRAF3IP3 TXLNA TXLNB TXLNG USE1 VAMP1 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VAPB VMA12 VTI1B ZFPL1	3 interacting genes: SNAP25 STX1A STX4
Entrez ID		6810	29091
HPRD ID		01722	06410
Ensembl ID		ENSG00000103496	ENSG00000168952
Uniprot IDs		B7Z425 Q12846	Q8NFX7
PDB IDs
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Membrane Fusion Syntaxin Binding Vesicle Fusion Organelle Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization SNARE Binding Vesicle Organization Exocytosis Organelle Localization By Membrane Tethering Establishment Of Localization In Cell Membrane Docking Secretion By Cell Vesicle Docking Protein Transport Secretion Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Golgi Vesicle Transport Cellular Localization Intracellular Protein Localization Intracellular Transport Organelle Localization Regulation Of Vesicle-mediated Transport Endomembrane System Calcium-ion Regulated Exocytosis SNARE Complex Assembly Membrane Regulated Exocytosis Regulation Of Exocytosis Syntaxin-1 Binding Synaptic Vesicle Exocytosis Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Intracellular Protein Transport Vesicle Fusion To Plasma Membrane Regulation Of Secretion By Cell Synaptic Vesicle Membrane Regulation Of Secretion Synaptic Vesicle Membrane Organization Signal Release Regulation Of Transport Regulation Of Regulated Secretory Pathway Synaptic Vesicle Calcium Ion-regulated Exocytosis Of Neurotransmitter Vesicle Docking Involved In Exocytosis Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Post-Golgi Vesicle-mediated Transport	SNARE Complex SNAP Receptor Activity SNARE Binding Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Neurotransmitter Transport Vesicle Fusion Organelle Membrane Fusion Organelle Fusion Positive Regulation Of Synaptic Transmission Membrane Fusion Regulation Of Insulin Secretion Synaptic Vesicle Docking Regulation Of Peptide Hormone Secretion Exocytosis SNARE Complex Assembly Somatodendritic Compartment Regulation Of Hormone Secretion Regulation Of Protein Secretion Vesicle Organization Neuron Projection Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Secretion By Cell Vesicle Docking Involved In Exocytosis Regulation Of Protein Transport Organelle Localization Modulation Of Chemical Synaptic Transmission Positive Regulation Of Regulated Secretory Pathway Secretion Regulation Of Establishment Of Protein Localization Regulation Of Hormone Levels Long-term Synaptic Potentiation Glutamatergic Synapse Regulation Of Secretion By Cell Regulation Of Secretion Membrane Organization Voltage-gated Potassium Channel Complex Calcium-dependent Protein Binding Positive Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Schaffer Collateral - CA1 Synapse Regulated Exocytosis Regulation Of Protein Localization Synapse Regulation Of Regulated Secretory Pathway Myosin Head/neck Binding Sphingomyelin Phosphodiesterase Activator Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?