RAB35 and IDH3B

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		RAB35	IDH3B
Name		RAB35, member RAS oncogene family	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
Structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Membrane Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Cytoplasmic Vesicle Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome	Nucleus Mitochondrion Mitochondrial Matrix Isocitrate Dehydrogenase Complex (NAD+)
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding Hydrolase Activity GDP Binding Metal Ion Binding	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Protein Binding Electron Transfer Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NAD Binding
	Biological Process	Mitotic Cytokinesis Intracellular Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus	Tricarboxylic Acid Cycle Isocitrate Metabolic Process
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Citric acid cycle (TCA cycle)
Drugs		None	NADH
Diseases		None	Retinitis pigmentosa (RP)
GWAS		Heel bone mineral density ( 30598549 )	No GWAS studies recorded
Interacting Genes		11 interacting genes: APP CALCOCO2 CBR3 DENND1B GNPAT IDH3B PTPRS TBPL1 TRIM54 USP32 WDCP	6 interacting genes: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35
Entrez ID		11021	3420
HPRD ID		05010	05163
Ensembl ID		ENSG00000111737	ENSG00000101365
Uniprot IDs		Q15286	A0A087WZN1 A0A087X2E5 O43837
PDB IDs		3TW8 6EKK 6IF2 6IF3	6KDE 6KDF 6KDY 6KE3 7CE3 8GRB 8GRD 8GRU 8GS5
GO Terms Enriched among Interactors		None	Isocitrate Dehydrogenase (NAD+) Activity Isocitrate Dehydrogenase Complex (NAD+) Isocitrate Metabolic Process Tricarboxylic Acid Metabolic Process Tricarboxylic Acid Cycle NAD Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor GATOR1 Complex Binding Septin Cytoskeleton Protein-arginine Omega-N Monomethyltransferase Activity N-methyltransferase Activity Histone H4R3 Methyltransferase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Cellular Response To Methionine Magnesium Ion Binding