RAB35 and USP32

Number of citations: 0 (PubMedID 36725886)
Data Source: BioGRID (enzymatic study)

		RAB35	USP32
Name		RAB35, member RAS oncogene family	ubiquitin specific peptidase 32
Structure			No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Membrane Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Cytoplasmic Vesicle Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Endomembrane System Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding Hydrolase Activity GDP Binding Metal Ion Binding	Cysteine-type Deubiquitinase Activity Calcium Ion Binding Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Mitotic Cytokinesis Intracellular Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus	Proteolysis Protein Deubiquitination Positive Regulation Of TORC1 Signaling
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	None
GWAS		Heel bone mineral density ( 30598549 )	Interleukin-6 levels ( 33517400 )
Novel Interactors		1 novel interactors: MPHOSPH9	None recorded
Interacting Genes		11 interacting genes: APP CALCOCO2 CBR3 DENND1B GNPAT IDH3B PTPRS TBPL1 TRIM54 USP32 WDCP	13 interacting genes: ANKRD29 DYRK1A MEOX2 MTNR1A NCK2 RAB35 RBCK1 RNF144A TRIM3 TRIM46 TRIM74 UBC ZDHHC17
Entrez ID		11021	84669
HPRD ID		05010	07612
Ensembl ID		ENSG00000111737	ENSG00000170832
Uniprot IDs		Q15286	Q8NFA0
PDB IDs		3TW8 6EKK 6IF2 6IF3	Not available
GO Terms Enriched among Interactors		None	Protein Modification Process Histone H3T45 Kinase Activity Endosome Membrane Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Modification-dependent Protein Catabolic Process Protein Modification By Small Protein Conjugation Immune System Process Ubiquitin Protein Ligase Activity Protein Polyubiquitination Ubiquitin-protein Transferase Activity Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Positive Regulation Of Anterograde Dense Core Granule Transport