RAB35 and CBR3

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		RAB35	CBR3
Name		RAB35, member RAS oncogene family	carbonyl reductase 3
Structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Membrane Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Cytoplasmic Vesicle Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome	Extracellular Space Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding Hydrolase Activity GDP Binding Metal Ion Binding	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity Carbonyl Reductase (NADPH) Activity Protein Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor NADPH Binding
	Biological Process	Mitotic Cytokinesis Intracellular Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Phase I - Functionalization of compounds
GWAS		Heel bone mineral density ( 30598549 )	Blood protein levels ( 30072576 ) Lumbar spine bone mineral density ( 22504420 )
Interacting Genes		11 interacting genes: APP CALCOCO2 CBR3 DENND1B GNPAT IDH3B PTPRS TBPL1 TRIM54 USP32 WDCP	7 interacting genes: ARIH2 BICD2 RAB35 RANBP9 S100A10 SDCBP UBC
Entrez ID		11021	874
HPRD ID		05010	07222
Ensembl ID		ENSG00000111737	ENSG00000159231
Uniprot IDs		Q15286	O75828 V9HW40
PDB IDs		3TW8 6EKK 6IF2 6IF3	2HRB
GO Terms Enriched among Interactors		None	Cytoskeletal Anchor Activity Plasma Membrane Apical Dendrite