RAB35 and WDCP

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		RAB35	WDCP
Name		RAB35, member RAS oncogene family	WD repeat and coiled coil containing
Structure			No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Membrane Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Cytoplasmic Vesicle Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome	None
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding Hydrolase Activity GDP Binding Metal Ion Binding	Protein Binding Kinase Binding
	Biological Process	Mitotic Cytokinesis Intracellular Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus	Protein Complex Oligomerization
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Signaling by ALK fusions and activated point mutants
GWAS		Heel bone mineral density ( 30598549 )	Feeling guilty ( 29500382 )
Novel Interactors		1 novel interactors: MPHOSPH9	1 novel interactors: DRC1
Interacting Genes		11 interacting genes: APP CALCOCO2 CBR3 DENND1B GNPAT IDH3B PTPRS TBPL1 TRIM54 USP32 WDCP	12 interacting genes: CSNK1E CSNK1G1 CSNK1G2 DYNC1I1 HCK MED31 PDPK1 PRKAR1A RAB35 RPS27 TAB1 TNNT1
Entrez ID		11021	80304
HPRD ID		05010	07972
Ensembl ID		ENSG00000111737	ENSG00000163026
Uniprot IDs		Q15286	Q9H6R7
PDB IDs		3TW8 6EKK 6IF2 6IF3	Not available
GO Terms Enriched among Interactors		None	Cytosol Protein Kinase Activity Nucleotide Binding Protein Serine Kinase Activity Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Protein Phosphorylation Phosphorylation Positive Regulation Of Wnt Signaling Pathway Protein Serine/threonine Kinase Activity Endocytosis Sarcomere Organization Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor Regulation Of Canonical Wnt Signaling Pathway 3-phosphoinositide-dependent Protein Kinase Activity Slow-twitch Skeletal Muscle Fiber Contraction Cellular Response To Growth Factor Stimulus Wnt Signaling Pathway Import Into Cell Positive Regulation Of Cell Communication Vesicle-mediated Transport Positive Regulation Of Signaling Response To Growth Factor Regulation Of Wnt Signaling Pathway Cell Surface Receptor Signaling Pathway