PTPRE and PTPRS

Number of citations of the paper that reports this interaction (PMID 12376545)
13

Data Source:
HPRD (in vivo)

		PTPRE	PTPRS
Gene Name		protein tyrosine phosphatase, receptor type, E	protein tyrosine phosphatase, receptor type, S
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Membrane	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Protein Homodimerization Activity	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Protein Dephosphorylation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Regulation Of Mast Cell Activation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway	Cell Adhesion Spinal Cord Development Cerebellum Development Hippocampus Development Cerebral Cortex Development Corpus Callosum Development Extracellular Matrix Organization Peptidyl-tyrosine Dephosphorylation
Pathways			ECM proteoglycans
Drugs
Diseases
GWAS		Response to amphetamines ( 22952603) Select biomarker traits ( 17903293)
Protein-Protein Interactions		10 interactors: FYN GRB2 KCNA5 KCNB1 MAPK1 MAPK3 PTPRD PTPRS SRC YES1	23 interactors: CHD3 EEF1G EGFR FEZ1 KAT5 KIAA1377 MOB4 PFN2 PPFIA1 PPFIA2 PPFIA3 PTN PTPRA PTPRD PTPRE PTPRM PTPRN RAB35 SETDB1 TUBB2A UBR1 UNC119 UTP14A
Entrez ID		5791	5802
HPRD ID		02956	03344
Ensembl ID		ENSG00000132334	ENSG00000105426
Uniprot IDs		P23469 Q96P81	Q13332 Q59FX6 Q8NHS7
PDB IDs		2JJD	2FH7 2YD2 2YD3 2YD9 4BPC
Enriched GO Terms of Interacting Partners?		Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Peptidyl-tyrosine Autophosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Axon Guidance Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Hemostasis Cellular Response To Fibroblast Growth Factor Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Platelet Activation Response To Fibroblast Growth Factor Response To Peptide Hormone Regulation Of Early Endosome To Late Endosome Transport Response To Platelet-derived Growth Factor Cellular Response To Organonitrogen Compound Immune Response-regulating Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Response To Peptide Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway T Cell Costimulation Axonogenesis Cellular Response To Growth Factor Stimulus Axon Development Cellular Response To Hormone Stimulus Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Response To Growth Factor Wound Healing Chemotaxis Neuron Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Positive Regulation Of Immune Response Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Cell Morphogenesis Involved In Differentiation Innate Immune Response Nervous System Development Neuron Projection Development	Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Glutamate Secretion Protein Dephosphorylation Acid Secretion Dephosphorylation Dicarboxylic Acid Transport Neurotransmitter Secretion Cellular Response To Estradiol Stimulus Regulation Of Neurotransmitter Levels Cellular Response To Estrogen Stimulus Positive Regulation Of Vasodilation Axon Guidance Amino Acid Transport Neuron Differentiation Neurotransmitter Transport Cell Projection Organization Signaling Cell Adhesion Cell Communication Regulation Of Vasodilation Neuron Projection Development Negative Regulation Of Epithelial Cell Migration Response To Estrogen Cell Projection Morphogenesis Cellular Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Cell Part Morphogenesis Secretion By Cell Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Cellular Response To Organic Substance Cell-cell Signaling Axonogenesis Cellular Response To Amino Acid Stimulus Regulation Of Stress Fiber Assembly Neuron Development Cellular Protein Modification Process Axon Development Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Astrocyte Activation Dense Core Granule Maturation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Regulation Of Dendrite Morphogenesis Chemotaxis Cell Cycle Process
Tagcloud ?		amplifications begin breakpoints copy csgalnact2 dataset dhx57 differing disruptions driver entity expand faf1 g34r h3f3a hgg icna intragenic k27m kcnd2 kidins220 map4k3 nf1 paediatric phgg rb1 ret suppressors tmem178	cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4
Tagcloud (Difference) ?		amplifications begin breakpoints copy csgalnact2 dataset dhx57 differing disruptions driver entity expand faf1 g34r h3f3a hgg icna intragenic k27m kcnd2 kidins220 map4k3 nf1 paediatric phgg rb1 ret suppressors tmem178	cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4
Tagcloud (Intersection) ?