PTPRD and PPFIA3

Number of citations of the paper that reports this interaction (PMID 9624153)
49

Data Source:
HPRD (in vitro)

		PTPRD	PPFIA3
Gene Name		protein tyrosine phosphatase, receptor type, D	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Cytosol Cell Surface Presynaptic Active Zone
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Receptor Binding Protein Binding Cell Adhesion Molecule Binding	Protein Binding
	Biological Process	Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Neuron Differentiation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Dendrite Morphogenesis Presynaptic Membrane Assembly	Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Regulation Of Short-term Neuronal Synaptic Plasticity
Pathways			Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661) Palmitic acid (16:0) plasma levels ( 23362303) Partial epilepsies ( 20522523) Platelet aggregation ( 20526338) Restless legs syndrome ( 18660810 21779176) Temperament ( 22832960) Type 2 diabetes ( 21647700 20174558)
Protein-Protein Interactions		8 interactors: MTSS1 PPFIA1 PPFIA2 PPFIA3 PTPRA PTPRE PTPRF PTPRS	12 interactors: CAST ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRG PTPRS PTPRU
Entrez ID		5789	8541
HPRD ID		03358	04393
Ensembl ID		ENSG00000153707	ENSG00000177380
Uniprot IDs		F5GWT7 P23468 Q2HXI4 Q3KPI9 Q59H90	O75145
PDB IDs		1X5Z 2DLH 2YD6 2YD7
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Acid Secretion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Dicarboxylic Acid Transport Neurotransmitter Secretion Dephosphorylation Regulation Of Neurotransmitter Levels Signaling Cell Communication Cell Adhesion Amino Acid Transport Neurotransmitter Transport Carboxylic Acid Transport Organic Acid Transport Enzyme Linked Receptor Protein Signaling Pathway Organic Anion Transport Secretion By Cell Adherens Junction Maintenance Synaptic Transmission Secretion Anion Transport Cell-matrix Adhesion Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Nephron Tubule Epithelial Cell Differentiation Microspike Assembly Signal Transduction Cell-substrate Adhesion Negative Regulation Of Receptor Binding Cell-cell Signaling Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Magnesium Ion Homeostasis Corpus Callosum Development Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Localization To Plasma Membrane Cellular Response To Stimulus Regulation Of Actin Filament-based Process Cellular Component Maintenance Phosphate-containing Compound Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Cytoskeleton Organization Regulation Of Mast Cell Activation Response To Fluid Shear Stress Negative Regulation Of Insulin Receptor Signaling Pathway	Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Cell Adhesion Enzyme Linked Receptor Protein Signaling Pathway Dephosphorylation Signaling Cell Communication Glutamate Secretion Signal Transduction Acid Secretion Dicarboxylic Acid Transport Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Amino Acid Transport Neurotransmitter Transport Cell-matrix Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Cell Migration Negative Regulation Of Receptor Binding Cell-substrate Adhesion Presynaptic Membrane Assembly Negative Regulation Of Cell Motility Phosphate-containing Compound Metabolic Process Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Cellular Component Movement Response To Stimulus Presynaptic Membrane Organization Negative Regulation Of Locomotion Negative Regulation Of Actin Filament Bundle Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Protein Modification Process Corpus Callosum Development Carboxylic Acid Transport Organic Acid Transport Protein Localization To Cell Surface Negative Regulation Of Protein Localization To Plasma Membrane Membrane Assembly RRNA Transcription Regulation Of Neuron Projection Development Nervous System Development Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Membrane Biogenesis
Tagcloud ?		alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools
Tagcloud (Difference) ?		alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools
Tagcloud (Intersection) ?