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PTPRD
Gene Name
protein tyrosine phosphatase, receptor type, D
Image
Gene Ontology Annotations
Cellular Component
Integral Component Of Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Receptor Binding
Protein Binding
Cell Adhesion Molecule Binding
Biological Process
Protein Dephosphorylation
Phosphate-containing Compound Metabolic Process
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Neuron Differentiation
Peptidyl-tyrosine Dephosphorylation
Positive Regulation Of Dendrite Morphogenesis
Presynaptic Membrane Assembly
Pathways
Drugs
Diseases
GWAS
Airflow obstruction (
22837378
)
Attention deficit hyperactivity disorder and conduct disorder (
18951430
)
Myopia (pathological) (
23049088
)
Obesity-related traits (
23251661
)
Palmitic acid (16:0) plasma levels (
23362303
)
Partial epilepsies (
20522523
)
Platelet aggregation (
20526338
)
Restless legs syndrome (
18660810
21779176
)
Temperament (
22832960
)
Type 2 diabetes (
21647700
20174558
)
Protein-protein Interactions
8 interactors:
MTSS1
PPFIA1
PPFIA2
PPFIA3
PTPRA
PTPRE
PTPRF
PTPRS
Entrez ID
5789
HPRD ID
03358
Ensembl ID
ENSG00000153707
Uniprot IDs
F5GWT7
P23468
Q2HXI4
Q3KPI9
Q59H90
PDB IDs
1X5Z
2DLH
2YD6
2YD7
Enriched GO Terms of Interacting Partners
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Glutamate Secretion
Peptidyl-tyrosine Dephosphorylation
Protein Dephosphorylation
Acid Secretion
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Dicarboxylic Acid Transport
Neurotransmitter Secretion
Dephosphorylation
Regulation Of Neurotransmitter Levels
Signaling
Cell Communication
Cell Adhesion
Amino Acid Transport
Neurotransmitter Transport
Carboxylic Acid Transport
Organic Acid Transport
Enzyme Linked Receptor Protein Signaling Pathway
Organic Anion Transport
Secretion By Cell
Adherens Junction Maintenance
Synaptic Transmission
Secretion
Anion Transport
Cell-matrix Adhesion
Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
Nephron Tubule Epithelial Cell Differentiation
Microspike Assembly
Signal Transduction
Cell-substrate Adhesion
Negative Regulation Of Receptor Binding
Cell-cell Signaling
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Actin Filament Bundle Assembly
Regulation Of Short-term Neuronal Synaptic Plasticity
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Magnesium Ion Homeostasis
Corpus Callosum Development
Cellular Response To Fluid Shear Stress
Glomerulus Morphogenesis
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of Protein Localization To Plasma Membrane
Cellular Response To Stimulus
Regulation Of Actin Filament-based Process
Cellular Component Maintenance
Phosphate-containing Compound Metabolic Process
Movement Of Cell Or Subcellular Component
Regulation Of Cytoskeleton Organization
Regulation Of Mast Cell Activation
Response To Fluid Shear Stress
Negative Regulation Of Insulin Receptor Signaling Pathway
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