PTPRD and PPFIA2

Number of citations of the paper that reports this interaction (PMID 9624153)
49

Data Source:
HPRD (in vitro)

		PTPRD	PPFIA2
Gene Name		protein tyrosine phosphatase, receptor type, D	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
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Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Cytoplasm Cytosol Cell Surface Presynaptic Active Zone Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Receptor Binding Protein Binding Cell Adhesion Molecule Binding	Protein Binding Protein Complex Binding
	Biological Process	Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Neuron Differentiation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Dendrite Morphogenesis Presynaptic Membrane Assembly	Cell-matrix Adhesion Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion
Pathways			Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661) Palmitic acid (16:0) plasma levels ( 23362303) Partial epilepsies ( 20522523) Platelet aggregation ( 20526338) Restless legs syndrome ( 18660810 21779176) Temperament ( 22832960) Type 2 diabetes ( 21647700 20174558)	Schizophrenia ( 22885689)
Protein-Protein Interactions		8 interactors: MTSS1 PPFIA1 PPFIA2 PPFIA3 PTPRA PTPRE PTPRF PTPRS	13 interactors: CAST CDC5L ERC2 GIT1 ITSN1 PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRG PTPRS
Entrez ID		5789	8499
HPRD ID		03358	04392
Ensembl ID		ENSG00000153707	ENSG00000139220
Uniprot IDs		F5GWT7 P23468 Q2HXI4 Q3KPI9 Q59H90	G3V200 O75334
PDB IDs		1X5Z 2DLH 2YD6 2YD7	3TAC 3TAD
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Acid Secretion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Dicarboxylic Acid Transport Neurotransmitter Secretion Dephosphorylation Regulation Of Neurotransmitter Levels Signaling Cell Communication Cell Adhesion Amino Acid Transport Neurotransmitter Transport Carboxylic Acid Transport Organic Acid Transport Enzyme Linked Receptor Protein Signaling Pathway Organic Anion Transport Secretion By Cell Adherens Junction Maintenance Synaptic Transmission Secretion Anion Transport Cell-matrix Adhesion Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Nephron Tubule Epithelial Cell Differentiation Microspike Assembly Signal Transduction Cell-substrate Adhesion Negative Regulation Of Receptor Binding Cell-cell Signaling Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Magnesium Ion Homeostasis Corpus Callosum Development Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Localization To Plasma Membrane Cellular Response To Stimulus Regulation Of Actin Filament-based Process Cellular Component Maintenance Phosphate-containing Compound Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Cytoskeleton Organization Regulation Of Mast Cell Activation Response To Fluid Shear Stress Negative Regulation Of Insulin Receptor Signaling Pathway	Peptidyl-tyrosine Dephosphorylation Enzyme Linked Receptor Protein Signaling Pathway Protein Dephosphorylation Signaling Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Communication Dephosphorylation Signal Transduction Glutamate Secretion Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Stimulus Acid Secretion Dicarboxylic Acid Transport Ephrin Receptor Signaling Pathway Neurotransmitter Secretion Cell Surface Receptor Signaling Pathway Response To Stimulus Regulation Of Neurotransmitter Levels Synaptic Transmission Nervous System Development Amino Acid Transport Neurotransmitter Transport Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Receptor Binding Presynaptic Membrane Assembly Generation Of Neurons Negative Regulation Of Stress Fiber Assembly Presynaptic Membrane Organization Neurogenesis Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of Cellular Process Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Cell-cell Signaling
Tagcloud ?		alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools
Tagcloud (Difference) ?		alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools
Tagcloud (Intersection) ?