PTPRD and MTSS1

Number of citations of the paper that reports this interaction (PMID 12570871)
28

Data Source:
HPRD (two hybrid, in vitro)

		PTPRD	MTSS1
Gene Name		protein tyrosine phosphatase, receptor type, D	metastasis suppressor 1
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Ruffle Cytoplasm Adherens Junction Actin Cytoskeleton Endocytic Vesicle
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Receptor Binding Protein Binding Cell Adhesion Molecule Binding	Actin Monomer Binding Receptor Binding Protein Binding Identical Protein Binding Actin Filament Binding
	Biological Process	Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Neuron Differentiation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Dendrite Morphogenesis Presynaptic Membrane Assembly	In Utero Embryonic Development Movement Of Cell Or Subcellular Component Plasma Membrane Organization Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Magnesium Ion Homeostasis Microspike Assembly Actin Cytoskeleton Organization Actin Filament Polymerization Bone Mineralization Positive Regulation Of Actin Filament Bundle Assembly Adherens Junction Maintenance Negative Regulation Of Epithelial Cell Proliferation Renal Tubule Morphogenesis Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
Pathways
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661) Palmitic acid (16:0) plasma levels ( 23362303) Partial epilepsies ( 20522523) Platelet aggregation ( 20526338) Restless legs syndrome ( 18660810 21779176) Temperament ( 22832960) Type 2 diabetes ( 21647700 20174558)
Protein-Protein Interactions		8 interactors: MTSS1 PPFIA1 PPFIA2 PPFIA3 PTPRA PTPRE PTPRF PTPRS	3 interactors: HTT PTPRD RECQL5
Entrez ID		5789	9788
HPRD ID		03358	12243
Ensembl ID		ENSG00000153707	ENSG00000170873
Uniprot IDs		F5GWT7 P23468 Q2HXI4 Q3KPI9 Q59H90	O43312
PDB IDs		1X5Z 2DLH 2YD6 2YD7	2D1K
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Acid Secretion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Dicarboxylic Acid Transport Neurotransmitter Secretion Dephosphorylation Regulation Of Neurotransmitter Levels Signaling Cell Communication Cell Adhesion Amino Acid Transport Neurotransmitter Transport Carboxylic Acid Transport Organic Acid Transport Enzyme Linked Receptor Protein Signaling Pathway Organic Anion Transport Secretion By Cell Adherens Junction Maintenance Synaptic Transmission Secretion Anion Transport Cell-matrix Adhesion Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Nephron Tubule Epithelial Cell Differentiation Microspike Assembly Signal Transduction Cell-substrate Adhesion Negative Regulation Of Receptor Binding Cell-cell Signaling Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Magnesium Ion Homeostasis Corpus Callosum Development Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Localization To Plasma Membrane Cellular Response To Stimulus Regulation Of Actin Filament-based Process Cellular Component Maintenance Phosphate-containing Compound Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Cytoskeleton Organization Regulation Of Mast Cell Activation Response To Fluid Shear Stress Negative Regulation Of Insulin Receptor Signaling Pathway	Neural Plate Formation Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Protein Phosphatase Type 2A Activity Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Lactate Biosynthetic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Paraxial Mesoderm Formation Quinolinate Metabolic Process Cellular Response To CGMP Response To CGMP Serotonin Transport Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Sperm Ejaculation Presynaptic Membrane Assembly Neural Plate Morphogenesis L-glutamate Import Presynaptic Membrane Organization Citrulline Metabolic Process Lactate Metabolic Process Urea Cycle Neurotransmitter Uptake Regulation Of Neuron Differentiation Urea Metabolic Process Thalamus Development Striatum Development Paraxial Mesoderm Morphogenesis Neural Plate Development Amino Acid Import Insemination Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of DNA-templated Transcription, Elongation Determination Of Adult Lifespan Mitotic Cell Cycle Process Grooming Behavior Regulation Of Neurogenesis Copulation Chromosome Separation Membrane Assembly Subpallium Development Mitotic Cell Cycle Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Monoamine Transport Paraxial Mesoderm Development Membrane Biogenesis L-glutamate Transport
Tagcloud ?		alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools	acetylated blocked cdna chip connexin connexin43 cx43 deacetylase diminishment fstl1 giant h4 hdac10 histones interestingly invasion lama4 metastasis mmp modulate modulating pg poorly recognized retarded s100a secreted transfection understood
Tagcloud (Difference) ?		alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools	acetylated blocked cdna chip connexin connexin43 cx43 deacetylase diminishment fstl1 giant h4 hdac10 histones interestingly invasion lama4 metastasis mmp modulate modulating pg poorly recognized retarded s100a secreted transfection understood
Tagcloud (Intersection) ?