PTPRD and PTPRA

Number of citations of the paper that reports this interaction (PMID 10777529)
13

Data Source:
HPRD (in vivo, two hybrid)

		PTPRD	PTPRA
Gene Name		protein tyrosine phosphatase, receptor type, D	protein tyrosine phosphatase, receptor type, A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Receptor Binding Protein Binding Cell Adhesion Molecule Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Neuron Differentiation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Dendrite Morphogenesis Presynaptic Membrane Assembly	Protein Phosphorylation Axon Guidance Insulin Receptor Signaling Pathway Peptidyl-tyrosine Dephosphorylation
Pathways			Axon guidance NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661) Palmitic acid (16:0) plasma levels ( 23362303) Partial epilepsies ( 20522523) Platelet aggregation ( 20526338) Restless legs syndrome ( 18660810 21779176) Temperament ( 22832960) Type 2 diabetes ( 21647700 20174558)
Protein-Protein Interactions		8 interactors: MTSS1 PPFIA1 PPFIA2 PPFIA3 PTPRA PTPRE PTPRF PTPRS	12 interactors: BCAR1 CALM1 FYN GABARAPL2 GRB2 KCNA2 PRKCD PTPRD PTPRF PTPRM PTPRS SRC
Entrez ID		5789	5786
HPRD ID		03358	01476
Ensembl ID		ENSG00000153707	ENSG00000132670
Uniprot IDs		F5GWT7 P23468 Q2HXI4 Q3KPI9 Q59H90	B7Z2A4 P18433
PDB IDs		1X5Z 2DLH 2YD6 2YD7
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Acid Secretion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Dicarboxylic Acid Transport Neurotransmitter Secretion Dephosphorylation Regulation Of Neurotransmitter Levels Signaling Cell Communication Cell Adhesion Amino Acid Transport Neurotransmitter Transport Carboxylic Acid Transport Organic Acid Transport Enzyme Linked Receptor Protein Signaling Pathway Organic Anion Transport Secretion By Cell Adherens Junction Maintenance Synaptic Transmission Secretion Anion Transport Cell-matrix Adhesion Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Nephron Tubule Epithelial Cell Differentiation Microspike Assembly Signal Transduction Cell-substrate Adhesion Negative Regulation Of Receptor Binding Cell-cell Signaling Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Magnesium Ion Homeostasis Corpus Callosum Development Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Localization To Plasma Membrane Cellular Response To Stimulus Regulation Of Actin Filament-based Process Cellular Component Maintenance Phosphate-containing Compound Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Cytoskeleton Organization Regulation Of Mast Cell Activation Response To Fluid Shear Stress Negative Regulation Of Insulin Receptor Signaling Pathway	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Platelet Activation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Blood Coagulation Hemostasis Cell Communication Immune Response-regulating Signaling Pathway Fc Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Growth Factor Wound Healing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Response To External Stimulus Cell Adhesion Response To Wounding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Peptidyl-tyrosine Dephosphorylation Signaling Regulation Of Immune Response Nervous System Development Protein Dephosphorylation Phagocytosis T Cell Costimulation Chemotaxis Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cellular Response To Stimulus Positive Regulation Of Immune Response Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Phosphate-containing Compound Metabolic Process Cellular Response To Peptide Locomotion Response To Platelet-derived Growth Factor Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Cell Surface Receptor Signaling Pathway
Tagcloud ?		alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools	aab antigens array auc autoantibodies autoantigens bead biomarkers contain curve igg luminex microarrays nappa nondiscriminating ovarian panel probed programmable ptgfr ranging retested sensitivities sera serous spauc specificity top twelve
Tagcloud (Difference) ?		alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools	aab antigens array auc autoantibodies autoantigens bead biomarkers contain curve igg luminex microarrays nappa nondiscriminating ovarian panel probed programmable ptgfr ranging retested sensitivities sera serous spauc specificity top twelve
Tagcloud (Intersection) ?