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TWF1 and ACTC1
Number of citations of the paper that reports this interaction (PMID
12207032
)
12
Data Source:
HPRD
(in vivo)
TWF1
ACTC1
Gene Name
twinfilin actin-binding protein 1
actin, alpha, cardiac muscle 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cell-cell Junction
Focal Adhesion
Actin Cytoskeleton
Myofibril
Filopodium
Ruffle Membrane
Perinuclear Region Of Cytoplasm
Extracellular Space
Cytoplasm
Cytosol
Actin Filament
Focal Adhesion
Membrane
Sarcomere
I Band
Actomyosin, Actin Portion
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
Actin Monomer Binding
Protein Tyrosine Kinase Activity
ATP Binding
Phosphatidylinositol-4,5-bisphosphate Binding
ATP Binding
ATPase Activity
Myosin Binding
Biological Process
Negative Regulation Of Actin Filament Polymerization
Sequestering Of Actin Monomers
Regulation Of Actin Phosphorylation
Apoptotic Process
Metabolic Process
Actin Filament-based Movement
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Actomyosin Structure Organization
Actin-myosin Filament Sliding
Response To Drug
Negative Regulation Of Apoptotic Process
Response To Ethanol
Cardiac Myofibril Assembly
Cardiac Muscle Tissue Morphogenesis
Heart Contraction
Cardiac Muscle Contraction
Pathways
Striated Muscle Contraction
Drugs
Diseases
GWAS
Prostate cancer (gene x gene interaction) (
22219177
)
Refractive error (
20835239
)
Protein-Protein Interactions
4 interactors:
ACTC1
APP
BMPR2
FBXO25
35 interactors:
ABLIM3
ABRA
ACTB
ACTN4
ACTR2
AFAP1
ANG
BCL11A
CAPN1
CFL1
DMD
DMTN
DYNLL1
EZR
FSCN1
GAPDH
GC
HSPB1
KLHL17
KLHL2
KPTN
LASP1
MIB2
MPC1
MYLK
PLEC
PRKCE
SCIN
SLC4A1
SYNE1
SYNE2
TNNI3K
TWF1
WAS
WIPF1
Entrez ID
5756
70
HPRD ID
10174
00015
Ensembl ID
ENSG00000151239
ENSG00000159251
Uniprot IDs
Q12792
B3KPP5
P68032
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Lung Blood Pressure
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Chondrocyte Proliferation
Collateral Sprouting In Absence Of Injury
Negative Regulation Of Vasoconstriction
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Developmental Growth
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Blood Circulation
Axon Choice Point Recognition
Skeletal Muscle Thin Filament Assembly
Positive Regulation Of Axon Extension Involved In Axon Guidance
Skeletal Myofibril Assembly
Lymphatic Endothelial Cell Differentiation
Neuron Remodeling
Cell Development
Lymphangiogenesis
Lymph Vessel Morphogenesis
Regulation Of Axon Extension Involved In Axon Guidance
Venous Blood Vessel Development
Cellular Copper Ion Homeostasis
Regulation Of Neuron Differentiation
Retina Vasculature Development In Camera-type Eye
Copper Ion Homeostasis
Suckling Behavior
Lymph Vessel Development
Regulation Of Growth
Negative Regulation Of Systemic Arterial Blood Pressure
Negative Regulation Of DNA Biosynthetic Process
Cardiac Myofibril Assembly
Anatomical Structure Morphogenesis
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Tissue Morphogenesis
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Regulation Of Neurogenesis
Activin Receptor Signaling Pathway
Actin-myosin Filament Sliding
Muscle Filament Sliding
Mating Behavior
Chondrocyte Development
Endoplasmic Reticulum Calcium Ion Homeostasis
Brain Development
RNA Polyadenylation
Neuron Recognition
Positive Regulation Of BMP Signaling Pathway
Head Development
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Actin Filament-based Process
Actin Cytoskeleton Organization
Cytoskeleton Organization
Actin Filament Organization
Organelle Organization
Movement Of Cell Or Subcellular Component
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Cellular Component Size
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Cytoskeleton Organization
Regulation Of Actin Cytoskeleton Organization
Cellular Component Assembly
Regulation Of Actin Filament-based Process
Regulation Of Cellular Component Organization
Actin Filament-based Movement
Phagocytosis
Blood Coagulation
Fc Receptor Signaling Pathway
Hemostasis
Cellular Localization
Actin Filament Bundle Assembly
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Organelle Organization
Regulation Of Actin Filament Polymerization
Actin Polymerization Or Depolymerization
Regulation Of Protein Complex Assembly
Platelet Activation
Regulation Of Sodium Ion Transmembrane Transporter Activity
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Cytoskeleton Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Regulation Of Sodium Ion Transmembrane Transport
Wound Healing
Positive Regulation Of Organelle Organization
Vesicle-mediated Transport
Endocytosis
Nucleus Localization
Negative Regulation Of Protein Complex Assembly
Maintenance Of Protein Location In Cell
Cell Activation
Positive Regulation Of Wound Healing
Maintenance Of Protein Location
Immune Response-regulating Signaling Pathway
Maintenance Of Location In Cell
Response To Wounding
Cell Projection Assembly
Tagcloud
?
accompany
ach3
ach4
cardiac
cardiomyocytes
cardiomyogenic
cd29
commitment
cscs
elusive
fate
hdac
hdac1
hdac2
hypothesize
indicative
loci
mark
modifications
mscs
myh6
myl2
noticed
possess
sca
stronger
tnni3
tnnt2
trichostatin
Tagcloud (Difference)
?
accompany
ach3
ach4
cardiac
cardiomyocytes
cardiomyogenic
cd29
commitment
cscs
elusive
fate
hdac
hdac1
hdac2
hypothesize
indicative
loci
mark
modifications
mscs
myh6
myl2
noticed
possess
sca
stronger
tnni3
tnnt2
trichostatin
Tagcloud (Intersection)
?