Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
EXOSC5 and BIRC2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
EXOSC5
BIRC2
Gene Name
exosome component 5
baculoviral IAP repeat containing 2
Image
Gene Ontology Annotations
Cellular Component
Exosome (RNase Complex)
Nucleus
Nucleolus
Cytoplasm
Cytosol
Transcriptionally Active Chromatin
XY Body
Nucleus
Cytoplasm
Cytosol
Spindle Microtubule
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Membrane Raft
Molecular Function
3'-5'-exoribonuclease Activity
RNA Binding
Exoribonuclease Activity
Protein Binding
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Protein N-terminus Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RRNA Processing
Gene Expression
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
DNA Deamination
Defense Response To Virus
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Protein Polyubiquitination
Response To Hypoxia
Placenta Development
Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell Surface Receptor Signaling Pathway
Regulation Of Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
NIK/NF-kappaB Signaling
Regulation Of RIG-I Signaling Pathway
Regulation Of Cell Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Regulation Of Innate Immune Response
Response To Ethanol
Regulation Of Cell Differentiation
Regulation Of Inflammatory Response
Protein Heterooligomerization
Response To CAMP
Regulation Of Cell Cycle
Regulation Of Necroptotic Process
Negative Regulation Of Necroptotic Process
Necroptotic Process
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Mitotic Spindle Assembly
Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process
Positive Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Protein K48-linked Ubiquitination
Positive Regulation Of Protein Monoubiquitination
Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Regulation of mRNA stability by proteins that bind AU-rich elements
KSRP destabilizes mRNA
mRNA decay by 3' to 5' exoribonuclease
ATF4 activates genes
Tristetraprolin (TTP) destabilizes mRNA
PERK regulates gene expression
Unfolded Protein Response (UPR)
Deadenylation-dependent mRNA decay
Butyrate Response Factor 1 (BRF1) destabilizes mRNA
Apoptotic cleavage of cellular proteins
IKK complex recruitment mediated by RIP1
TRIF-mediated TLR3/TLR4 signaling
Apoptotic execution phase
MyD88-independent cascade
Activated TLR4 signalling
Toll-Like Receptors Cascades
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
NOD1/2 Signaling Pathway
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
Programmed Cell Death
Innate Immune System
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
32 interactors:
BIRC2
CALCOCO2
CDK5RAP1
DHRS2
DIS3
DOCK8
EXOSC1
EXOSC10
EXOSC2
EXOSC3
EXOSC6
EXOSC7
EXOSC8
EXOSC9
FCHO1
GOLGA2
IKZF3
KIAA1217
KRT13
LIPG
LSM5
MPP6
NUP210
PA2G4
PKM
POLR2L
REL
SFPQ
SKIV2L2
TNFAIP1
TRIM54
ZNF558
58 interactors:
BIRC5
BIRC7
BOLA1
CASP2
CASP3
CASP7
CASP9
CBLC
CD40
DIABLO
DZIP3
EAF2
EXOSC5
FBXO7
GAS1
GCC1
GFAP
GSPT1
HSP90B1
HTRA2
IKBKE
IKBKG
JUP
LTBR
MAGEA11
MAP3K2
MAP3K3
NMB
OTUB1
PACS2
PCSK9
PPM1K
RAC1
RAF1
RHOA
RIPK1
RIPK2
RIPK3
RIPK4
RNF181
TRADD
TRAF1
TRAF2
TRIM34
TSG101
TSGA10
UBB
UBC
UBE2B
UBE2D1
UBE2D2
UBE2D3
UBE2J1
UBE2Q2
UBE2S
UBE2V1
UBE2W
WDYHV1
Entrez ID
56915
329
HPRD ID
16222
03419
Ensembl ID
ENSG00000077348
ENSG00000110330
Uniprot IDs
M0R050
Q9NQT4
Q13490
PDB IDs
2NN6
1QBH
2L9M
3D9T
3D9U
3M1D
3MUP
3OZ1
3T6P
3UW4
4EB9
4HY4
4HY5
4LGE
4LGU
Enriched GO Terms of Interacting Partners
?
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
RRNA Processing
RRNA Metabolic Process
Ribosome Biogenesis
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
NcRNA Metabolic Process
Nuclear-transcribed MRNA Catabolic Process
Ribonucleoprotein Complex Biogenesis
MRNA Catabolic Process
RNA Catabolic Process
MRNA Metabolic Process
RRNA Catabolic Process
Nuclear Polyadenylation-dependent RRNA Catabolic Process
CUT Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
RNA Metabolic Process
Maturation Of 5.8S RRNA
Nuclear MRNA Surveillance
Aromatic Compound Catabolic Process
RNA Surveillance
Cellular Macromolecule Catabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
RNA Phosphodiester Bond Hydrolysis
Cellular Nitrogen Compound Metabolic Process
Catabolic Process
Nitrogen Compound Metabolic Process
Intracellular MRNA Localization
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Polyadenylation-dependent SnoRNA 3'-end Processing
Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription
U4 SnRNA 3'-end Processing
Nucleic Acid Phosphodiester Bond Hydrolysis
TRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5'
RNA Processing
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
SnoRNA Metabolic Process
RRNA 3'-end Processing
Cellular Metabolic Process
RNA Localization
DNA Deamination
Immune System Process
Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Immune Response
Leukocyte Activation
Isotype Switching
Programmed Cell Death
Cell Death
Death
Apoptotic Process
Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Activation Of Innate Immune Response
Regulation Of Protein Metabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Apoptotic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of Innate Immune Response
Protein Ubiquitination
Cellular Response To Stress
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Positive Regulation Of Cellular Protein Metabolic Process
Protein Polyubiquitination
Protein Processing
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Innate Immune Response
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Signal Transduction
Protein Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cell Death
Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Transferase Activity
Response To Stress
Cellular Protein Catabolic Process
Cellular Protein Modification Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Positive Regulation Of Cellular Metabolic Process
Cellular Protein Metabolic Process
Tagcloud
?
2b
arrest
baculoviral
c4
caspases
cdk2
ciap1
consumer
deacetylases
dependently
du
ester
hdacs
immortalized
lncap
maa
malformation
methoxyacetic
named
p63
p73
pharmaceutical
phthalates
prns
prostatic
rwpe
spermatocyte
suppresses
turning
Tagcloud (Difference)
?
2b
arrest
baculoviral
c4
caspases
cdk2
ciap1
consumer
deacetylases
dependently
du
ester
hdacs
immortalized
lncap
maa
malformation
methoxyacetic
named
p63
p73
pharmaceutical
phthalates
prns
prostatic
rwpe
spermatocyte
suppresses
turning
Tagcloud (Intersection)
?