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BIRC2 and RNF181
Number of citations of the paper that reports this interaction (PMID
22493164
)
2
Data Source:
BioGRID
(two hybrid)
BIRC2
RNF181
Gene Name
baculoviral IAP repeat containing 2
ring finger protein 181
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
XY Body
Nucleus
Cytoplasm
Cytosol
Spindle Microtubule
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Membrane Raft
Molecular Function
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Protein N-terminus Binding
Ubiquitin-protein Transferase Activity
Zinc Ion Binding
Ligase Activity
Biological Process
Protein Polyubiquitination
Response To Hypoxia
Placenta Development
Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell Surface Receptor Signaling Pathway
Regulation Of Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
NIK/NF-kappaB Signaling
Regulation Of RIG-I Signaling Pathway
Regulation Of Cell Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Regulation Of Innate Immune Response
Response To Ethanol
Regulation Of Cell Differentiation
Regulation Of Inflammatory Response
Protein Heterooligomerization
Response To CAMP
Regulation Of Cell Cycle
Regulation Of Necroptotic Process
Negative Regulation Of Necroptotic Process
Necroptotic Process
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Mitotic Spindle Assembly
Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process
Positive Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Protein K48-linked Ubiquitination
Positive Regulation Of Protein Monoubiquitination
Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Reactive Oxygen Species Metabolic Process
Protein Autoubiquitination
Pathways
Apoptotic cleavage of cellular proteins
IKK complex recruitment mediated by RIP1
TRIF-mediated TLR3/TLR4 signaling
Apoptotic execution phase
MyD88-independent cascade
Activated TLR4 signalling
Toll-Like Receptors Cascades
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
NOD1/2 Signaling Pathway
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
Programmed Cell Death
Innate Immune System
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Prostate cancer (
21743467
)
Protein-Protein Interactions
58 interactors:
BIRC5
BIRC7
BOLA1
CASP2
CASP3
CASP7
CASP9
CBLC
CD40
DIABLO
DZIP3
EAF2
EXOSC5
FBXO7
GAS1
GCC1
GFAP
GSPT1
HSP90B1
HTRA2
IKBKE
IKBKG
JUP
LTBR
MAGEA11
MAP3K2
MAP3K3
NMB
OTUB1
PACS2
PCSK9
PPM1K
RAC1
RAF1
RHOA
RIPK1
RIPK2
RIPK3
RIPK4
RNF181
TRADD
TRAF1
TRAF2
TRIM34
TSG101
TSGA10
UBB
UBC
UBE2B
UBE2D1
UBE2D2
UBE2D3
UBE2J1
UBE2Q2
UBE2S
UBE2V1
UBE2W
WDYHV1
19 interactors:
BIRC2
BTG1
CLK4
MRPS6
NPY5R
PEG10
RBCK1
TRIM24
TRIM8
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UBE2U
VPS11
ZMYND10
Entrez ID
329
51255
HPRD ID
03419
14236
Ensembl ID
ENSG00000110330
Uniprot IDs
Q13490
Q9P0P0
PDB IDs
1QBH
2L9M
3D9T
3D9U
3M1D
3MUP
3OZ1
3T6P
3UW4
4EB9
4HY4
4HY5
4LGE
4LGU
Enriched GO Terms of Interacting Partners
?
Programmed Cell Death
Cell Death
Death
Apoptotic Process
Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Activation Of Innate Immune Response
Regulation Of Protein Metabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Apoptotic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of Innate Immune Response
Protein Ubiquitination
Cellular Response To Stress
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Positive Regulation Of Cellular Protein Metabolic Process
Protein Polyubiquitination
Protein Processing
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Innate Immune Response
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Signal Transduction
Protein Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cell Death
Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Transferase Activity
Response To Stress
Cellular Protein Catabolic Process
Cellular Protein Modification Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Positive Regulation Of Cellular Metabolic Process
Cellular Protein Metabolic Process
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein K48-linked Ubiquitination
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Toll-like Receptor 4 Signaling Pathway
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Cellular Protein Modification Process
Activation Of Innate Immune Response
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Cellular Macromolecule Catabolic Process
Cellular Protein Metabolic Process
Positive Regulation Of Innate Immune Response
Protein K11-linked Ubiquitination
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Immune Response-regulating Signaling Pathway
Regulation Of Innate Immune Response
Cellular Response To Oxygen Levels
Response To Hypoxia
Catabolic Process
Positive Regulation Of Protein Ubiquitination
Protein Metabolic Process
Positive Regulation Of Immune Response
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Proteolysis
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Innate Immune Response
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Ligase Activity
Negative Regulation Of Necroptotic Process
Tagcloud
?
2b
arrest
baculoviral
c4
caspases
cdk2
ciap1
consumer
deacetylases
dependently
du
ester
hdacs
immortalized
lncap
maa
malformation
methoxyacetic
named
p63
p73
pharmaceutical
phthalates
prns
prostatic
rwpe
spermatocyte
suppresses
turning
Tagcloud (Difference)
?
2b
arrest
baculoviral
c4
caspases
cdk2
ciap1
consumer
deacetylases
dependently
du
ester
hdacs
immortalized
lncap
maa
malformation
methoxyacetic
named
p63
p73
pharmaceutical
phthalates
prns
prostatic
rwpe
spermatocyte
suppresses
turning
Tagcloud (Intersection)
?