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EXOSC5 and GOLGA2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
EXOSC5
GOLGA2
Gene Name
exosome component 5
golgin A2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Exosome (RNase Complex)
Nucleus
Nucleolus
Cytoplasm
Cytosol
Transcriptionally Active Chromatin
Golgi Membrane
Nucleus
Golgi Apparatus
Cis-Golgi Network
ER To Golgi Transport Vesicle
Golgi Cisterna Membrane
Molecular Function
3'-5'-exoribonuclease Activity
RNA Binding
Exoribonuclease Activity
Protein Binding
Protein Binding
Protein Kinase Binding
Syntaxin Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RRNA Processing
Gene Expression
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
DNA Deamination
Defense Response To Virus
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Mitotic Cell Cycle
Negative Regulation Of Protein Binding
Pathways
Regulation of mRNA stability by proteins that bind AU-rich elements
KSRP destabilizes mRNA
mRNA decay by 3' to 5' exoribonuclease
ATF4 activates genes
Tristetraprolin (TTP) destabilizes mRNA
PERK regulates gene expression
Unfolded Protein Response (UPR)
Deadenylation-dependent mRNA decay
Butyrate Response Factor 1 (BRF1) destabilizes mRNA
Mitotic Prophase
Golgi Cisternae Pericentriolar Stack Reorganization
Cell Cycle, Mitotic
M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions
32 interactors:
BIRC2
CALCOCO2
CDK5RAP1
DHRS2
DIS3
DOCK8
EXOSC1
EXOSC10
EXOSC2
EXOSC3
EXOSC6
EXOSC7
EXOSC8
EXOSC9
FCHO1
GOLGA2
IKZF3
KIAA1217
KRT13
LIPG
LSM5
MPP6
NUP210
PA2G4
PKM
POLR2L
REL
SFPQ
SKIV2L2
TNFAIP1
TRIM54
ZNF558
281 interactors:
ABLIM1
ADAP1
AES
AFF4
ALKBH3
ALS2CR11
AMOTL2
ANKRD11
ANKRD36BP1
APC
ARID5A
ARL16
ARL4A
ARNT2
ARPC3
ATP6V1C2
ATP6V1D
ATP6V1G1
ATXN7
BAHD1
BARD1
BCAS2
BCL6B
BMS1P5
BYSL
C12orf50
C14orf105
C1orf109
C1orf35
C20orf195
CBX8
CCAR1
CCDC146
CCDC150
CCDC17
CCDC53
CCDC67
CCDC70
CCDC87
CCDC94
CCHCR1
CCNC
CCNH
CDC20B
CDC5L
CDC73
CDK1
CDK18
CDKL3
CENPP
CEP57L1
CHCHD2
CHCHD3
CINP
CORO1A
CRMP1
CSPP1
CUL5
CYB5R2
DAXX
DCTN4
DCX
DDX6
DGCR6
DLGAP5
DLX6-AS1
DMTN
DTX2
EIF3G
EP300
EXOSC5
FAM110A
FAM124B
FAM126B
FAM184A
FAM193B
FAM207A
FAM214A
FAM50B
FAM90A1
FBF1
FBXL18
FBXO28
FIP1L1
GATA2
GATAD2B
GCC1
GEM
GFAP
GLYCTK
GNG5
GORASP1
GORASP2
GPANK1
GPKOW
GPS2
GSE1
GTPBP10
GZMA
GZMK
HAUS1
HDAC4
HOXB9
HRASLS5
HTRA1
HYLS1
IFT20
IFT27
INPP5J
IQCE
ISCU
ITPKB
ITSN2
KANK2
KANSL1
KAT5
KDM1A
KIAA1217
KIFC3
KRT18
KRT6A
KRT6B
KRT6C
LASP1
LATS1
LCOR
LCP2
LENG1
LGALS3
LIMS2
LIN7A
LINGO1
LMO1
LMO2
LMO4
LYPLA1
LYSMD1
MAB21L2
MAGOH
MAGOHB
MBD3
MCM10
MCM7
MFAP1
MID2
MORF4L1
MORF4L2
MORN3
MOS
MSRB3
MTFR2
MVP
MYEF2
NCF2
NDE1
NDEL1
NDN
NEBL
NME7
NOS3
NUDT21
NXT2
ORC1
PARD6B
PATL1
PIAS2
PID1
PIK3R2
PIN1
PKN1
PKP4
POLDIP3
POM121
PPP1R16B
PPP1R18
PPP2CA
PQBP1
PRKAA1
PRKAB2
PRPF31
PSMA1
PSMA4
RAB1A
RAB1B
RAB2A
RAB2B
RAB33B
RAB39A
RAB39B
RAB6A
RBL1
RBM17
RBM39
RBM41
RCOR3
RGS8
RHNO1
RIBC1
RITA1
RNF135
RNF213
RNF214
RSPH14
RSRC2
RTP5
RUSC2
SAMD4A
SAP30BP
SCAF8
SCEL
SCNM1
SECISBP2
SELV
SH2D4A
SH3RF2
SHC3
SLU7
SMARCE1
SMCP
SNAP47
SNF8
SNRPB
SNRPB2
SNRPC
SNTA1
SNW1
SPATA2
SPATA22
SRSF2
STAMBPL1
STK25
STK26
SYT6
TBP
TCEA2
TCEANC
TCF19
TCL1A
TEAD4
TFAP4
THAP7
TMED2
TPM1
TPX2
TRIM29
TRIM42
TSC22D4
TSSC4
TSSK3
TTC23
TTC25
TTC9C
TUBGCP4
TXLNA
UBE2I
UBE2U
UBE3C
USO1
USP2
UTP14C
VPS28
VPS37C
WDYHV1
YTHDC1
ZBTB16
ZFC3H1
ZFP2
ZFYVE26
ZGPAT
ZMAT2
ZNF124
ZNF250
ZNF410
ZNF414
ZNF417
ZNF488
ZNF572
ZNF581
ZNF587
ZNF594
ZNF774
Entrez ID
56915
2801
HPRD ID
16222
03989
Ensembl ID
ENSG00000077348
ENSG00000167110
Uniprot IDs
M0R050
Q9NQT4
Q08379
PDB IDs
2NN6
Enriched GO Terms of Interacting Partners
?
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
RRNA Processing
RRNA Metabolic Process
Ribosome Biogenesis
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
NcRNA Metabolic Process
Nuclear-transcribed MRNA Catabolic Process
Ribonucleoprotein Complex Biogenesis
MRNA Catabolic Process
RNA Catabolic Process
MRNA Metabolic Process
RRNA Catabolic Process
Nuclear Polyadenylation-dependent RRNA Catabolic Process
CUT Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
RNA Metabolic Process
Maturation Of 5.8S RRNA
Nuclear MRNA Surveillance
Aromatic Compound Catabolic Process
RNA Surveillance
Cellular Macromolecule Catabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
RNA Phosphodiester Bond Hydrolysis
Cellular Nitrogen Compound Metabolic Process
Catabolic Process
Nitrogen Compound Metabolic Process
Intracellular MRNA Localization
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Polyadenylation-dependent SnoRNA 3'-end Processing
Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription
U4 SnRNA 3'-end Processing
Nucleic Acid Phosphodiester Bond Hydrolysis
TRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5'
RNA Processing
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
SnoRNA Metabolic Process
RRNA 3'-end Processing
Cellular Metabolic Process
RNA Localization
DNA Deamination
Immune System Process
Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Immune Response
Leukocyte Activation
Isotype Switching
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cell Cycle
Organelle Organization
Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
MRNA Metabolic Process
MRNA Processing
RNA Splicing
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Mitotic Cell Cycle
RNA Processing
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Negative Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Cellular Metabolic Process
Regulation Of Cellular Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Cell Cycle
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Rab Protein Signal Transduction
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Gene Expression
Cell Cycle Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Transcription, DNA-templated
Cellular Process
Phagosome Maturation
Chromosome Organization
Cellular Component Assembly
Chromatin Modification
Chromatin Organization
Mitotic Cell Cycle Process
Mitotic Cell Cycle Phase Transition
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cell Cycle Phase Transition
Tagcloud
?
5p
accounts
ameliorated
ap1
canx
chaperones
clamp
decoy
deleterious
deregulation
disturbances
electrical
eliminated
erg
forced
former
h2o2
hek293
hsc70
micrornas
mirnas
myocytes
patch
reciprocal
record
seed
sequestration
trafficking
upregulation
Tagcloud (Difference)
?
5p
accounts
ameliorated
ap1
canx
chaperones
clamp
decoy
deleterious
deregulation
disturbances
electrical
eliminated
erg
forced
former
h2o2
hek293
hsc70
micrornas
mirnas
myocytes
patch
reciprocal
record
seed
sequestration
trafficking
upregulation
Tagcloud (Intersection)
?