NDNL2 and PJA1

Number of citations of the paper that reports this interaction (PMID 20864041)
40

Data Source:
BioGRID (affinity chromatography technology, pull down)

		NDNL2	PJA1
Gene Name		necdin-like 2	praja ring finger 1, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Cytoplasm Smc5-Smc6 Complex	Cytoplasm
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	DNA Repair DNA Recombination Positive Regulation Of Protein Ubiquitination Regulation Of Growth	Protein Ubiquitination Protein Catabolic Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: E2F1 EID3 NGFR PJA1 TRIM28	36 interactors: ASCC2 ATP5C1 ATXN3 ATXN3L EED ESPL1 EZH2 GSR HNRNPL JOSD1 KIF22 MAGED1 MDM2 NDN NDNL2 OTUB1 OTUB2 RIBC2 SPTBN1 STAM STAMBP SUZ12 UBC UBE2D2 UBE2D3 UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP7 USP8 ZNF440
Entrez ID		56160	64219
HPRD ID		10503	02335
Ensembl ID		ENSG00000185115	ENSG00000181191
Uniprot IDs		Q96MG7	Q8NG27
PDB IDs		3NW0	2L0B
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Fibroblast Proliferation Regulation Of Fibroblast Proliferation Negative Regulation Of DNA Demethylation Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Hair Follicle Development Positive Regulation Of Apoptotic Signaling Pathway Lens Fiber Cell Apoptotic Process Negative Regulation Of Hair Cycle Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Convergent Extension Involved In Axis Elongation Positive Regulation Of Intracellular Transport Organ Development Regulation Of Genetic Imprinting DNA Methylation Involved In Embryo Development Anoikis Apoptotic Signaling Pathway Positive Regulation Of Odontogenesis Cellular Response To Stress Convergent Extension Negative Regulation Of Viral Release From Host Cell Regulation Of Intracellular Transport Regulation Of Odontogenesis Of Dentin-containing Tooth Membrane Protein Intracellular Domain Proteolysis Regulation Of Hair Follicle Development System Development Regulation Of Glucose Import In Response To Insulin Stimulus Morphogenesis Of An Epithelium Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Hair Cycle Regulation Of Viral Release From Host Cell Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Protein Sumoylation MRNA Stabilization Embryonic Placenta Morphogenesis Protein Ubiquitination Positive Regulation Of Apoptotic Process Detection Of Temperature Stimulus Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Programmed Cell Death DNA Repair Regulation Of Odontogenesis Protein Modification By Small Protein Conjugation Positive Regulation Of Cell Death Multicellular Organismal Development Tissue Morphogenesis Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Axis Elongation Hair Follicle Morphogenesis	Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process DNA Repair Cellular Response To Stress Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Proteolysis Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone Modification Cell Cycle Process Metabolic Process Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromosome Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Ubiquitination Cell Cycle Cytokinesis Protein Modification By Small Protein Conjugation Chromatin Modification Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?