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NDNL2 and TRIM28
Number of citations of the paper that reports this interaction (PMID
20864041
)
40
Data Source:
BioGRID
(pull down)
NDNL2
TRIM28
Gene Name
necdin-like 2
tripartite motif containing 28
Image
Gene Ontology Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Cytoplasm
Smc5-Smc6 Complex
Nucleus
Nucleoplasm
Nuclear Euchromatin
Nuclear Heterochromatin
RNA Polymerase II Transcription Factor Complex
Molecular Function
Protein Binding
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Kinase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Krueppel-associated Box Domain Binding
Sequence-specific DNA Binding
Poly(A) RNA Binding
Chromo Shadow Domain Binding
Biological Process
DNA Repair
DNA Recombination
Positive Regulation Of Protein Ubiquitination
Regulation Of Growth
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Epithelial To Mesenchymal Transition
DNA Repair
Transcription Initiation From RNA Polymerase II Promoter
Embryo Implantation
Gene Expression
Protein Ubiquitination
Protein Sumoylation
Positive Regulation Of Transcription Factor Import Into Nucleus
DNA Methylation Involved In Embryo Development
Innate Immune Response
Positive Regulation Of DNA Repair
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Protein Autophosphorylation
Protein Oligomerization
Convergent Extension Involved In Axis Elongation
Embryonic Placenta Morphogenesis
Negative Regulation Of DNA Demethylation
Negative Regulation Of Viral Release From Host Cell
Regulation Of Genetic Imprinting
Pathways
Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions
5 interactors:
E2F1
EID3
NGFR
PJA1
TRIM28
62 interactors:
CBX1
CBX3
CBX5
CDC34
CDCA4
CEBPB
CHAF1A
CHD3
ESR1
FES
HDAC10
HTRA2
IRF1
IRF7
LYN
MAGEA2
MAGEA2B
MAGEA3
MAGEA6
MAGED1
MYB
NDNL2
NR3C1
NR4A1
NR4A3
PFDN5
PPP4C
RNF4
SENP7
SERTAD1
SERTAD2
SETDB1
SIN3A
SKI
SMARCAD1
SPG7
STAT3
TRIM24
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2H
UBE2I
UBE2L3
UBE2N
UBE2U
VHL
VIM
YWHAQ
ZNF10
ZNF133
ZNF140
ZNF197
ZNF354A
ZNF382
ZNF420
ZNF496
ZNF689
ZNF74
Entrez ID
56160
10155
HPRD ID
10503
03445
Ensembl ID
ENSG00000185115
ENSG00000130726
Uniprot IDs
Q96MG7
Q13263
PDB IDs
3NW0
1FP0
2RO1
2YVR
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Fibroblast Proliferation
Regulation Of Fibroblast Proliferation
Negative Regulation Of DNA Demethylation
Cellular Response To DNA Damage Stimulus
Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Hair Follicle Development
Positive Regulation Of Apoptotic Signaling Pathway
Lens Fiber Cell Apoptotic Process
Negative Regulation Of Hair Cycle
Positive Regulation Of Odontogenesis Of Dentin-containing Tooth
Convergent Extension Involved In Axis Elongation
Positive Regulation Of Intracellular Transport
Organ Development
Regulation Of Genetic Imprinting
DNA Methylation Involved In Embryo Development
Anoikis
Apoptotic Signaling Pathway
Positive Regulation Of Odontogenesis
Cellular Response To Stress
Convergent Extension
Negative Regulation Of Viral Release From Host Cell
Regulation Of Intracellular Transport
Regulation Of Odontogenesis Of Dentin-containing Tooth
Membrane Protein Intracellular Domain Proteolysis
Regulation Of Hair Follicle Development
System Development
Regulation Of Glucose Import In Response To Insulin Stimulus
Morphogenesis Of An Epithelium
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Regulation Of Hair Cycle
Regulation Of Viral Release From Host Cell
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Protein Sumoylation
MRNA Stabilization
Embryonic Placenta Morphogenesis
Protein Ubiquitination
Positive Regulation Of Apoptotic Process
Detection Of Temperature Stimulus
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Programmed Cell Death
DNA Repair
Regulation Of Odontogenesis
Protein Modification By Small Protein Conjugation
Positive Regulation Of Cell Death
Multicellular Organismal Development
Tissue Morphogenesis
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Axis Elongation
Hair Follicle Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Regulation Of Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Protein K48-linked Ubiquitination
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Macromolecule Biosynthetic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Protein Polyubiquitination
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Protein Catabolic Process
Cellular Metabolic Process
Regulation Of Cellular Process
Cellular Protein Catabolic Process
Positive Regulation Of Metabolic Process
Protein Ubiquitination
Biosynthetic Process
Protein Modification By Small Protein Conjugation
Protein K11-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Gene Expression
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Regulation Of Ubiquitin-protein Transferase Activity
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Tagcloud
?
accumulates
aging
becoming
damaged
depletion
genomes
il6
il8
ink4a
insults
kap1
knocked
krab
limits
mediating
mixture
ois
oncogene
partially
pathologies
prevented
profound
reinforcing
sasp
secrete
secretory
senescence
termed
undergo
Tagcloud (Difference)
?
accumulates
aging
becoming
damaged
depletion
genomes
il6
il8
ink4a
insults
kap1
knocked
krab
limits
mediating
mixture
ois
oncogene
partially
pathologies
prevented
profound
reinforcing
sasp
secrete
secretory
senescence
termed
undergo
Tagcloud (Intersection)
?