PSENEN and PSEN1

  • Number of citations of the paper that reports this interaction (PMID 12198112)
  • 41
  • Data Source:
  • HPRD (in vitro, in vivo)

PSENEN

PSEN1

Gene Name presenilin enhancer gamma secretase subunit presenilin 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 6 interactors: APH1A NCSTN PSEN1 PSEN2 THBD TMED10 91 interactors: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DLL1 DOCK3 DSP ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RHEB RMDN3 RNF32 SCAF11 SCN1A ST13 STAMBPL1 TCF4 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1
Entrez ID 55851 5663
HPRD ID 06362 00087
Ensembl ID ENSG00000080815
Uniprot IDs Q9NZ42 P49768
PDB IDs 2KR6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ad  al  amyloidosis  attenuates  burden  ca1  calorie  cerebral  cr  endogenously  enhancer  feeding  female  hippocampal  indicates  influences  intake  involve  libitum  neuron  pathology  reduces  reductions  restriction  secretase  sustained  tg2576  translatable 
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
Tagcloud (Difference) ?
ad  al  amyloidosis  attenuates  burden  ca1  calorie  cerebral  cr  endogenously  enhancer  feeding  female  hippocampal  indicates  influences  intake  involve  libitum  neuron  pathology  reduces  reductions  restriction  secretase  sustained  tg2576  translatable 
1795g  2125g  abeta37  abeta39  abeta40  advance  dementia  dementias  doi  e599k  ejhg  fus  g709s  genetics  genotyping  granulin  grn  harbored  hek293  journal  lewy  mapt  neuropathological  pd  publically  publication  shifted  tar  variants 
Tagcloud (Intersection) ?