MARK3 and CPSF4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		MARK3	CPSF4
Gene Name		MAP/microtubule affinity-regulating kinase 3	cleavage and polyadenylation specific factor 4, 30kDa
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Extracellular Vesicular Exosome	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Protein Phosphorylation	MRNA Processing Modulation By Virus Of Host Morphology Or Physiology Modulation By Virus Of Host Process Viral Life Cycle Modification By Virus Of Host MRNA Processing
Pathways			Inhibition of Host mRNA Processing and RNA Silencing Host Interactions with Influenza Factors Influenza Infection NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Bone mineral density ( 22504420)
Protein-Protein Interactions		27 interactors: ANKRD7 ASB13 ATP6V0C CDC25C CHGB CPSF4 DYNLL1 FANCF HDAC7 KSR1 MAP2 MAPT MITF NOL11 PIM1 PKP2 PMPCB PNPLA2 PRKCQ SAAL1 SFN TCEA2 TTR VPS11 YWHAG YWHAQ YWHAZ	5 interactors: FIP1L1 MARK3 MEOX2 RRAGA SLC12A9
Entrez ID		4140	10898
HPRD ID		04058	04338
Ensembl ID		ENSG00000075413	ENSG00000160917
Uniprot IDs		P27448 Q86U11	O95639
PDB IDs		2QNJ 3FE3	2D9N 2RHK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Apoptotic Process Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Programmed Cell Death Cell Death Death Organelle Organization Apoptotic Signaling Pathway Regulation Of Organelle Organization Regulation Of Apoptotic Process Positive Regulation Of Transport Regulation Of Cellular Component Organization Regulation Of Cell Death Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Signal Transduction G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Apoptotic Process Multicellular Organismal Development Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death System Development Intracellular Signal Transduction Regulation Of Cellular Localization Regulation Of Establishment Of Protein Localization Substantia Nigra Development Protein Targeting Regulation Of Protein Localization Developmental Process Cellular Response To Insulin Stimulus Neural Nucleus Development Signaling Anatomical Structure Development Regulation Of Phosphorylation Protein Targeting To Mitochondrion Regulation Of Cellular Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Intracellular Protein Transport Cell Communication Negative Regulation Of Apoptotic Process Positive Regulation Of T-helper 2 Cell Activation
Tagcloud ?		acrylamide amiloride bbmv benzoyl border brush cariporide dihydro guanidine guanidino hnhe1 ic50 isopro isopropyl lap1 methane methylsulphonyl micromol nhe nhe1 nhe2 nhe3 ok opossum propenyl pylidene rbnhe2 s3226 sulphonate	abcb1 akap9 c1orf16 cacna1e cyp51a1 est ests ets1 fnbp2 glul gnai1 gusb imprh inra inraschp mapkapk2 pepp3 positional ptgs2 qtl rab7l1 robo4 sgce siat4c ssc3 ssc9 steap thg zoo
Tagcloud (Difference) ?		acrylamide amiloride bbmv benzoyl border brush cariporide dihydro guanidine guanidino hnhe1 ic50 isopro isopropyl lap1 methane methylsulphonyl micromol nhe nhe1 nhe2 nhe3 ok opossum propenyl pylidene rbnhe2 s3226 sulphonate	abcb1 akap9 c1orf16 cacna1e cyp51a1 est ests ets1 fnbp2 glul gnai1 gusb imprh inra inraschp mapkapk2 pepp3 positional ptgs2 qtl rab7l1 robo4 sgce siat4c ssc3 ssc9 steap thg zoo
Tagcloud (Intersection) ?