ATF3 and ID3

Number of citations of the paper that reports this interaction (PMID 18255255)
1

Data Source:
BioGRID (two hybrid)

		ATF3	ID3
Gene Name		activating transcription factor 3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Gluconeogenesis Transcription, DNA-templated Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cell Proliferation Endoplasmic Reticulum Unfolded Protein Response Skeletal Muscle Cell Differentiation Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription From RNA Polymerase II Promoter Metanephros Development Regulation Of DNA Replication Transcription, DNA-templated Multicellular Organismal Development Central Nervous System Development Heart Development Muscle Organ Development Circadian Rhythm Response To Wounding Neuron Differentiation Epithelial Cell Differentiation Notochord Development Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle
Pathways		ATF4 activates genes PERK regulates gene expression Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		41 interactors: ATF2 ATF4 BATF BATF3 CEBPA CEBPE CEBPG CREB3 CREBBP DBP DDIT3 FGFR3 FOS FOSL1 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 ID3 IGSF21 JUN JUNB JUND LRIF1 MAFF MAFG MDM2 NFKB1 NUF2 PDX1 POLR3D SMAD3 SRA1 SS18L1 STAT1 SUMO1 SUMO3 SUV39H1 TP53 ZNF212	36 interactors: ADD1 ATF3 CBFA2T2 CDK2 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626
Entrez ID		467	3399
HPRD ID		04395	02608
Ensembl ID		ENSG00000162772	ENSG00000117318
Uniprot IDs		P18847	Q02535
PDB IDs			2LFH
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Stress Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Cellular Metabolic Process Response To Organic Substance Regulation Of Cell Differentiation Response To External Stimulus Negative Regulation Of Cellular Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Defense Response Cellular Response To Organic Substance Cell Differentiation Immune System Process Histone H3-K9 Modification Developmental Process Rhythmic Process Regulation Of Cell Death Response To Biotic Stimulus	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Muscle Structure Development Skeletal Muscle Cell Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Fiber Development Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Cell Fate Commitment Negative Regulation Of Transcription From RNA Polymerase II Promoter Striated Muscle Tissue Development Multicellular Organismal Development Muscle Cell Differentiation Muscle Tissue Development Negative Regulation Of Cellular Metabolic Process Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Organ Development
Tagcloud ?		activating attenuation beneficial caat chop combating contributes diabetogenic dietary elevation elicited endoplasmic enhancer evoked fatty hdac1 hdac3 homologous islets lipotoxicity mimicked min6 ms palmitate preserving prevents reticulum saturated silencing	accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Difference) ?		activating attenuation beneficial caat chop combating contributes diabetogenic dietary elevation elicited endoplasmic enhancer evoked fatty hdac1 hdac3 homologous islets lipotoxicity mimicked min6 ms palmitate preserving prevents reticulum saturated silencing	accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Intersection) ?