NACA and LRIF1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NACA	LRIF1
Gene Name		nascent polypeptide-associated complex alpha subunit	ligand dependent nuclear receptor interacting factor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nascent Polypeptide-associated Complex Extracellular Vesicular Exosome	Nucleus Microtubule Organizing Center Actin Cytoskeleton Nuclear Matrix
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding TBP-class Protein Binding	Protein Binding Retinoic Acid Receptor Binding
	Biological Process	Cardiac Ventricle Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Negative Regulation Of Striated Muscle Cell Apoptotic Process Protein Transport Viral Process Skeletal Muscle Tissue Regeneration Positive Regulation Of Skeletal Muscle Tissue Growth Regulation Of Skeletal Muscle Fiber Development Heart Trabecula Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: APLP1 BTF3 CCDC90B FADD FOS FUNDC2 IGSF21 JUN LRIF1 MDM2 NUPR1 SMYD1 SPP1 TBP TXLNA UCHL5 ZHX1	129 interactors: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRADD CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 HAP1 HIST3H3 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NHP2L1 NOC2L NR3C1 NRBP1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR2C POLR3F PPARG PQBP1 PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSPAN6 UBE2V2 VIM WDR62 WWC1 ZNF24
Entrez ID		4666	55791
HPRD ID		03137	17975
Ensembl ID		ENSG00000196531	ENSG00000121931
Uniprot IDs		B2R4P8 Q13765	Q5T3J3
PDB IDs		3LKX 3MCB 3MCE
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Skeletal Muscle Cell Differentiation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Myeloid Cell Differentiation Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Regulation Of Myeloid Leukocyte Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Nucleobase-containing Compound Metabolic Process Skeletal Muscle Tissue Development Cellular Macromolecule Biosynthetic Process Activation Of Innate Immune Response Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Defense Response Macromolecule Biosynthetic Process Skeletal Muscle Organ Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Response To Organic Cyclic Compound Response To Extracellular Stimulus Immune Response-regulating Signaling Pathway Immune System Process Regulation Of Myeloid Cell Differentiation Organ Development Response To Toxic Substance Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Innate Immune Response Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Response To Reactive Oxygen Species Apoptotic Process Programmed Cell Death Cellular Response To Extracellular Stimulus Response To Mechanical Stimulus	Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Gene Expression Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Protein Metabolic Process System Development Regulation Of Gene Expression Developmental Process Regulation Of Cellular Protein Metabolic Process RNA Metabolic Process Multicellular Organismal Development Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Anatomical Structure Development Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cell Death Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Response To Stimulus Nervous System Development Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Macromolecule Biosynthetic Process Response To Organic Substance Cellular Metabolic Process Response To Stress Positive Regulation Of Apoptotic Process Response To Steroid Hormone Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus DNA-templated Transcription, Initiation Regulation Of Cell Cycle Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Organic Substance Regulation Of Cell Cycle
Tagcloud ?		ap apd20 apd50 apd90 atrial caf cal calibrate calibrated determines deviating electrophysiology explaining hampering inter ionic ito k1 kur mimic nak recordings rhythm sr trabeculae triangulation underlies variability yielding	aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate
Tagcloud (Difference) ?		ap apd20 apd50 apd90 atrial caf cal calibrate calibrated determines deviating electrophysiology explaining hampering inter ionic ito k1 kur mimic nak recordings rhythm sr trabeculae triangulation underlies variability yielding	aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate
Tagcloud (Intersection) ?