NACA

Gene Name		nascent polypeptide-associated complex alpha subunit
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nascent Polypeptide-associated Complex Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding TBP-class Protein Binding
	Biological Process	Cardiac Ventricle Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Negative Regulation Of Striated Muscle Cell Apoptotic Process Protein Transport Viral Process Skeletal Muscle Tissue Regeneration Positive Regulation Of Skeletal Muscle Tissue Growth Regulation Of Skeletal Muscle Fiber Development Heart Trabecula Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		17 interactors: APLP1 BTF3 CCDC90B FADD FOS FUNDC2 IGSF21 JUN LRIF1 MDM2 NUPR1 SMYD1 SPP1 TBP TXLNA UCHL5 ZHX1
Entrez ID		4666
HPRD ID		03137
Ensembl ID		ENSG00000196531
Uniprot IDs		B2R4P8 Q13765
PDB IDs		3LKX 3MCB 3MCE
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Skeletal Muscle Cell Differentiation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Myeloid Cell Differentiation Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Regulation Of Myeloid Leukocyte Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Nucleobase-containing Compound Metabolic Process Skeletal Muscle Tissue Development Cellular Macromolecule Biosynthetic Process Activation Of Innate Immune Response Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Defense Response Macromolecule Biosynthetic Process Skeletal Muscle Organ Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Response To Organic Cyclic Compound Response To Extracellular Stimulus Immune Response-regulating Signaling Pathway Immune System Process Regulation Of Myeloid Cell Differentiation Organ Development Response To Toxic Substance Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Innate Immune Response Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Response To Reactive Oxygen Species Apoptotic Process Programmed Cell Death Cellular Response To Extracellular Stimulus Response To Mechanical Stimulus
Tagcloud ?		ap apd20 apd50 apd90 atrial caf cal calibrate calibrated determines deviating electrophysiology explaining hampering inter ionic ito k1 kur mimic nak recordings rhythm sr trabeculae triangulation underlies variability yielding