MAP7D1 and COPS6

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		MAP7D1	COPS6
Gene Name		MAP7 domain containing 1	COP9 signalosome subunit 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Spindle Microtubule	Nucleoplasm Cytoplasm COP9 Signalosome Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization	Cullin Deneddylation Viral Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APOA1 ATN1 COPS6 GPRASP1 RBM48	84 interactors: ANXA1 ANXA7 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 JUN LAMA4 LPL MAP7D1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 VIM WIPI2 ZEB2 ZNF24
Entrez ID		55700	10980
HPRD ID		07666	16735
Ensembl ID		ENSG00000116871	ENSG00000168090
Uniprot IDs		Q3KQU3	Q7L5N1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Adhesion Molecule Production G-protein Coupled Receptor Catabolic Process Negative Regulation Of Interleukin-1 Beta Secretion Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Negative Regulation Of Interleukin-1 Secretion High-density Lipoprotein Particle Clearance Protein Oxidation Negative Regulation Of Heterotypic Cell-cell Adhesion Negative Regulation Of Cytokine Secretion Involved In Immune Response High-density Lipoprotein Particle Assembly Cullin Deneddylation Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Cholesterol Esterification Regulation Of Intestinal Cholesterol Absorption Phospholipid Homeostasis Peptidyl-methionine Modification Regulation Of Cholesterol Esterification Protein Deneddylation Peripheral Nervous System Axon Regeneration Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Maintenance Of Cell Polarity Phospholipid Efflux Regulation Of Cytokine Secretion Involved In Immune Response Toxin Metabolic Process Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity Negative Regulation Of Interleukin-1 Beta Production Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway High-density Lipoprotein Particle Remodeling Glucocorticoid Metabolic Process Protein-lipid Complex Assembly Endothelial Cell Proliferation Reverse Cholesterol Transport Negative Chemotaxis Receptor Catabolic Process Negative Regulation Of Lipase Activity Regulation Of Interleukin-1 Beta Secretion Phosphatidylcholine Biosynthetic Process Positive Regulation Of Lipid Catabolic Process Plasma Lipoprotein Particle Remodeling Positive Regulation Of Steroid Metabolic Process Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Cholesterol Efflux Regulation Of Cdc42 Protein Signal Transduction Endosome To Lysosome Transport Positive Regulation Of Fatty Acid Metabolic Process Blood Vessel Endothelial Cell Migration Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Fatty Acid Biosynthetic Process	Cullin Deneddylation Protein Deneddylation Developmental Process Intrinsic Apoptotic Signaling Pathway Cellular Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Catalytic Activity Tissue Development Mitotic Cell Cycle Programmed Cell Death Apoptotic Signaling Pathway Response To Stress Cell Death Catabolic Process Death Regulation Of Cell Proliferation Mitotic Cell Cycle Process Cellular Response To Stress Response To Abiotic Stimulus G1/S Transition Of Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Phosphorylation Response To Organic Cyclic Compound Cell Cycle Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Cycle Organ Development Multicellular Organismal Development Epithelium Development Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Death Response To Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Programmed Cell Death System Development Negative Regulation Of Cell Death Cellular Macromolecule Catabolic Process Response To Organic Substance Regulation Of Protein Kinase Activity Positive Regulation Of Cell Death
Tagcloud ?			aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Difference) ?			aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Intersection) ?